| Literature DB >> 30197225 |
Hossein Derakhshandeh1, Sara Saheb Kashaf2, Fariba Aghabaglou1, Ian O Ghanavati1, Ali Tamayol3.
Abstract
Chronic non-healing wounds are major healthcare challenges that affect a noticeable number of people; they exert a severe financial burden and are the leading cause of limb amputation. Although chronic wounds are locked in a persisting inflamed state, they are dynamic and proper therapy requires identifying abnormalities, administering proper drugs and growth factors, and modulating the conditions of the environment. In this review article, we discuss technologies that have been developed to actively monitor the wound environment. We also highlight drug delivery tools that have been integrated with bandages to facilitate precise temporal and spatial control over drug release and review automated or semi-automated systems that can respond to the wound environment.Entities:
Keywords: drug delivery; flexible electronics; integrated systems; smart bandages; wound care
Mesh:
Year: 2018 PMID: 30197225 PMCID: PMC6511580 DOI: 10.1016/j.tibtech.2018.07.007
Source DB: PubMed Journal: Trends Biotechnol ISSN: 0167-7799 Impact factor: 19.536