Literature DB >> 30196551

Analysis of clinical outcomes of upper and lower extremity reconstructions in patients with soft-tissue sarcoma.

Trishul Kapoor1, Joseph Banuelos1, Kian Adabi1, Steven L Moran1, Oscar J Manrique1.   

Abstract

BACKGROUND AND OBJECTIVES: Primary amputations have been the standard of treatment for extremity soft tissue sarcomas. However, over the last few decades, this mode of treatment has been increasingly replaced by limb-sparing procedures.1 Our goal is to report the clinical outcomes of upper and lower extremity reconstructions in patients with a history of soft-tissue sarcoma.
METHODS: A retrospective review of 178 patients with a history of soft-tissue sarcoma who underwent upper or lower extremity reconstructions was conducted. Demographics, tumor characteristics, treatment modalities, type of flap utilized, functional outcomes, and postoperative donor-/recipient-site complications (DSC/RSC) were analyzed. Variables were compared between free and pedicle flaps (FF or PF).
RESULTS: PF reconstructions had a higher rate of DSC (P < 0.044), whereas FF reconstructions had a higher rate of RSC (P < 0.03). Upper extremity reconstruction resulted in a mean QuickDASH score of 5.98 (SD 9.37) with no significant difference between PF and FF. Lower extremity reconstruction resulted in a mean score of 71.2 (SD 10.7) for PF and 71.3 (SD 5.1) for FF on the Lower Extremity Function Scale.
CONCLUSION: Limb-preserving reconstruction with PF and FF is a reliable and safe option after sarcoma resection. In addition, long-term outcomes are promising and reassure the adequate functionality of the limb.
© 2018 Wiley Periodicals, Inc.

Entities:  

Keywords:  limb reconstruction; patient outcomes; sarcoma

Mesh:

Year:  2018        PMID: 30196551     DOI: 10.1002/jso.25201

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  4 in total

1.  Upper Extremity Free Flap Transfers: An Analysis of the National Surgical Quality Improvement Program Database.

Authors:  George A Beyer; Karan Dua; Neil V Shah; Joseph P Scollan; Jared M Newman; Suhail K Mithani; Steven M Koehler
Journal:  J Hand Microsurg       Date:  2020-09-22

2.  Free Tissue Transfer during the COVID-19 Pandemic: A Proposed Evidence-Based Protocol for Early Discharge.

Authors:  Matthew E Pontell; Alexandra L Alving-Trinh; Sara Chaker; Julian S Winocour; Wesley P Thayer
Journal:  World J Plast Surg       Date:  2022-03

3.  Soft-tissue reconstruction after soft-tissue sarcoma resection: the clinical outcomes of 24 patients.

Authors:  Hideo Hasegawa; Shinji Tsukamoto; Kanya Honoki; Takamasa Shimizu; Lorenzo Ferra; Costantino Errani; Spyros Sioutis; Andreas F Mavrogenis; Yasuhito Tanaka
Journal:  Eur J Orthop Surg Traumatol       Date:  2021-02-20

4.  Patient's quality of life after surgery and radiotherapy for extremity soft tissue sarcoma - a retrospective single-center study over ten years.

Authors:  Rebekka Götzl; Sebastian Sterzinger; Sabine Semrau; Nikolaos Vassos; Werner Hohenberger; Robert Grützmann; Abbas Agaimy; Andreas Arkudas; Raymund E Horch; Justus P Beier
Journal:  Health Qual Life Outcomes       Date:  2019-11-08       Impact factor: 3.186

  4 in total

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