Literature DB >> 30193126

An Unexpected Calm: Mfge8 Controls Stem Cell Quiescence and Maintenance.

Tomohiko Okazaki1, Yukiko Gotoh2.   

Abstract

Radial glia-like neural stem cells (RGLs) in the mouse hippocampus generate neurons throughout life, but RGL maintenance mechanisms remain unclear. In this issue of Cell Stem Cell, Zhou et al. (2018) identified Mfge8, a well-known mediator of the "eat-me" signal, as a factor that reinforces quiescence and protects the RGL niche from depletion.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 30193126     DOI: 10.1016/j.stem.2018.08.006

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN: 1875-9777            Impact factor:   24.633


  1 in total

1.  Increased MFG-E8 at neuromuscular junctions is an exacerbating factor for sarcopenia-associated denervation.

Authors:  Madoka Ikemoto-Uezumi; Heying Zhou; Tamaki Kurosawa; Yuki Yoshimoto; Masashi Toyoda; Nobuo Kanazawa; Tatsu Nakazawa; Mitsuhiro Morita; Kunihiro Tsuchida; Akiyoshi Uezumi
Journal:  Aging Cell       Date:  2021-12-24       Impact factor: 9.304

  1 in total

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