Literature DB >> 30191341

In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance.

Yasuhiro Tsume1,2, Sanjaykumar Patel3, Nikoletta Fotaki4, Christel Bergstrӧm5, Gordon L Amidon6, James G Brasseur7, Deanna M Mudie8, Duxin Sun6, Marival Bermejo9, Ping Gao10, Wei Zhu11, David C Sperry12, Maria Vertzoni13, Neil Parrott14, Robert Lionberger15, Atsushi Kambayashi16, Andre Hermans11, Xujin Lu17, Gregory E Amidon6.   

Abstract

Entities:  

Keywords:  dissolution; formulation prediction; in vivo prediction; simulation

Mesh：

Substances：

Year:  2018        PMID： 30191341      PMCID： PMC8830932          DOI： 10.1208/s12248-018-0260-3

Source DB:  PubMed          Journal:  AAPS J        ISSN： 1550-7416            Impact factor:   4.009


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  41 in total

1.  The impact of reduced gastric acid secretion on dissolution of salts of weak bases in the fasted upper gastrointestinal lumen: Data in biorelevant media and in human aspirates.

Authors:  Chara Litou; Maria Vertzoni; Wei Xu; Filippos Kesisoglou; Christos Reppas
Journal:  Eur J Pharm Biopharm       Date:  2017-02-16       Impact factor: 5.571

2.  Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs.

Authors:  Bart Hens; Yasuhiro Tsume; Marival Bermejo; Paulo Paixao; Mark J Koenigsknecht; Jason R Baker; William L Hasler; Robert Lionberger; Jianghong Fan; Joseph Dickens; Kerby Shedden; Bo Wen; Jeffrey Wysocki; Raimar Loebenberg; Allen Lee; Ann Frances; Greg Amidon; Alex Yu; Gail Benninghoff; Niloufar Salehi; Arjang Talattof; Duxin Sun; Gordon L Amidon
Journal:  Mol Pharm       Date:  2017-08-04       Impact factor: 4.939

3.  Characterization of Contents of Distal Ileum and Cecum to Which Drugs/Drug Products are Exposed During Bioavailability/Bioequivalence Studies in Healthy Adults.

Authors:  Christos Reppas; Eleni Karatza; Constantinos Goumas; Constantinos Markopoulos; Maria Vertzoni
Journal:  Pharm Res       Date:  2015-05-22       Impact factor: 4.200

4.  The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS).

Authors:  Yasuhiro Tsume; Kazuki Matsui; Amanda L Searls; Susumu Takeuchi; Gregory E Amidon; Duxin Sun; Gordon L Amidon
Journal:  Eur J Pharm Sci       Date:  2017-03-03       Impact factor: 4.384

5.  In silico prediction of drug dissolution and absorption with variation in intestinal pH for BCS class II weak acid drugs: ibuprofen and ketoprofen.

Authors:  Yasuhiro Tsume; Peter Langguth; Alfredo Garcia-Arieta; Gordon L Amidon
Journal:  Biopharm Drug Dispos       Date:  2012-08-21       Impact factor: 1.627

6.  Matching phosphate and maleate buffer systems for dissolution of weak acids: Equivalence in terms of buffer capacity of bulk solution or surface pH?

Authors:  Rodrigo Cristofoletti; Jennifer B Dressman
Journal:  Eur J Pharm Biopharm       Date:  2016-03-23       Impact factor: 5.571

7.  Impact of Drug-Rich Colloids of Itraconazole and HPMCAS on Membrane Flux in Vitro and Oral Bioavailability in Rats.

Authors:  Aaron M Stewart; Michael E Grass; Timothy J Brodeur; Aaron K Goodwin; Michael M Morgen; Dwayne T Friesen; David T Vodak
Journal:  Mol Pharm       Date:  2017-06-22       Impact factor: 4.939

8.  A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability.

Authors:  G L Amidon; H Lennernäs; V P Shah; J R Crison
Journal:  Pharm Res       Date:  1995-03       Impact factor: 4.200

9.  In vivo predictive dissolution: transport analysis of the CO2 , bicarbonate in vivo buffer system.

Authors:  Brian J Krieg; Seyed Mohammad Taghavi; Gordon L Amidon; Gregory E Amidon
Journal:  J Pharm Sci       Date:  2014-09-11       Impact factor: 3.534

10.  Pharmaceutical characterisation and evaluation of cocrystals: Importance of in vitro dissolution conditions and type of coformer.

Authors:  Irena Tomaszewska; Shyam Karki; Jag Shur; Robert Price; Nikoletta Fotaki
Journal:  Int J Pharm       Date:  2013-05-29       Impact factor: 5.875
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  1 in total

Review 1.  Current trends in drug metabolism and pharmacokinetics.

Authors:  Yuhua Li; Qiang Meng; Mengbi Yang; Dongyang Liu; Xiangyu Hou; Lan Tang; Xin Wang; Yuanfeng Lyu; Xiaoyan Chen; Kexin Liu; Ai-Ming Yu; Zhong Zuo; Huichang Bi
Journal:  Acta Pharm Sin B       Date:  2019-10-18       Impact factor: 11.413
  1 in total

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