Sanjay Rastogi1, Rupshikha Choudhury2, Ashish Kumar3, Shiva Manjunath4, Aanchal Sood5, Himanshu Upadhyay6. 1. Dept. of Oral and Maxillofacial Surgery, Teerthankar Mahaveer Dental College and Research Center, Moradabad, UP, India. 2. Dept. of Oral and Maxillofacial Surgery, Regional Dental College, Guwahati, Assam, India, India. 3. Dept. of Public Health Dentistry, BJS, Dental College, Ludhiana, Punjab, India. 4. Dept. of Periodontology, Institute of Dental Sciences, Bareilly, UP, India. 5. Dept. of Periodontics, BJS Dental College and Research Center, Ludhiana, Punjab, India. 6. Dept. of Oral and Maxillofacial Surgery, Institute of Dental Sciences, Bareilly, UP, India.
Abstract
OBJECTIVE: To assess the efficacy of Platelet Rich Fibrin (PRF) on the pain and healing of the extraction socket associated with Alveolar Osteitis (Dry Socket, AO) after removal of maxillary and mandibular molars. STUDY DESIGN: 100 adult patients with age group ranging from 18 to 40 years along with established dry socket after maxillary and mandibular molar extractions who have not received any treatment for the same were included in the study. PRF was placed in the maxillary and mandibular molar extraction sockets after adequate irrigation of the socket. All the patients evaluated for the various study variables which include pain, degree of inflammation, and healthy granulation tissue formation at 1st, 3rd, 7th, and 14th post operative day. Data were analyzed using Shapirowilk's test, chi square test and/or student-t test, Friedman's test, Wilcoxson's signed rank test, and Bonferroni test, with the significance level set at P < 0.05. RESULTS: There was significant reduction in pain associated with AO at the 3rd and 7th postoperative day along with better wound healing by the end of 2nd week. CONCLUSION: Use of PRF in this study illustrates the promising results in terms of reduced pain and better healing in the patients with Alveolar Osteitits.
OBJECTIVE: To assess the efficacy of Platelet Rich Fibrin (PRF) on the pain and healing of the extraction socket associated with Alveolar Osteitis (Dry Socket, AO) after removal of maxillary and mandibular molars. STUDY DESIGN: 100 adult patients with age group ranging from 18 to 40 years along with established dry socket after maxillary and mandibular molar extractions who have not received any treatment for the same were included in the study. PRF was placed in the maxillary and mandibular molar extraction sockets after adequate irrigation of the socket. All the patients evaluated for the various study variables which include pain, degree of inflammation, and healthy granulation tissue formation at 1st, 3rd, 7th, and 14th post operative day. Data were analyzed using Shapirowilk's test, chi square test and/or student-t test, Friedman's test, Wilcoxson's signed rank test, and Bonferroni test, with the significance level set at P < 0.05. RESULTS: There was significant reduction in pain associated with AO at the 3rd and 7th postoperative day along with better wound healing by the end of 2nd week. CONCLUSION: Use of PRF in this study illustrates the promising results in terms of reduced pain and better healing in the patients with Alveolar Osteitits.
Authors: David M Dohan; Joseph Choukroun; Antoine Diss; Steve L Dohan; Anthony J J Dohan; Jaafar Mouhyi; Bruno Gogly Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Date: 2006-03