Nidhi Jain1, Anil Kumar Nagarajappa2,3, Meenakshi Bhasin4, Divya Pandya5, Kaushal Pati Tripathi6. 1. Dept. of Oral Medicine and Radiology, Hitkarini Dental College and Hospital, Girls Hostel, Room # 204, Hitkarini Hills, Dumna Road, Jabalpur, M.P., 482005, India. 2. Former HOD Dept. of Oral Medicine and Radiology, Hitkarini Dental College and Hospital, Hitkarini Hills, Dumna Road, Jabalpur, M.P., 482005, India. 3. Currently Lecturer at Dep. of Oral Medicine and Radiology, College of Dentistry, Al-Jouf University, Sakaka, Zip Code: 42421, Kingdom of Saudi Arabia. 4. Dep. of Oral Medicine and Radiology, Hitkarini Dental College and Hospital, Hitkarini Hills, Dumna Road, Jabalpur, M.P., 482005, India. 5. Jabalpur Hospital and Research Centre, F2 Atul Vihar II SBI Colony Near Hathitaal Railway Crossing, Gorakhpur, Jabalpur, M.P., India. 6. Dept. of Peiodontology and Implantology, Hitkarini Dental College and Hospital, Boys Hostel, Room # 26, Hitkarini Hills, Dumna Road, Jabalpur, M.P., 482005, India.
Abstract
OBJECTIVES: To assess the efficacy of Chemiluminescent light (Vizilite plus) in enhancing visualization and its ability to highlight Leukoplakia lesion. MATERIAL AND METHODS: This was a cross-sectional study done on 40 study subjects. Subjects were inducted into the study irrespective of age and sex based on the specific inclusion and exclusion criteria. The lesion parameters like the location of the lesion, the shape of lesion, the size, the extent, borders and the presence or absence of any adjacent satellite lesions were assessed under Incandescent light followed by Toluidine blue and Vizilite plus examinations. Histopathological examination results were considered as the gold standard and TBLU and CHEM outcomes were compared to them. RESULTS: Vizilite plus examination method was most effective in assessing the size, borders and shape of the lesions followed by Toluidine blue and Incandescent light examinations. Toluidine blue and Vizilite plus examination methods demonstrated the sensitivity of 100% and specificity of 97.3%. They also demonstrated PPV of 100% and NPV of 75% with reliable accuracy of 97.5%. CONCLUSION: Chemiluminescent light is a stepping stone and has the potential to revolutionize the diagnostic protocol for patients with potentially premalignant lesions. The device can be used as a general oral mucosal examination system and may in particular improve the visualization of potentially premalignant lesions.
OBJECTIVES: To assess the efficacy of Chemiluminescent light (Vizilite plus) in enhancing visualization and its ability to highlight Leukoplakia lesion. MATERIAL AND METHODS: This was a cross-sectional study done on 40 study subjects. Subjects were inducted into the study irrespective of age and sex based on the specific inclusion and exclusion criteria. The lesion parameters like the location of the lesion, the shape of lesion, the size, the extent, borders and the presence or absence of any adjacent satellite lesions were assessed under Incandescent light followed by Toluidine blue and Vizilite plus examinations. Histopathological examination results were considered as the gold standard and TBLU and CHEM outcomes were compared to them. RESULTS: Vizilite plus examination method was most effective in assessing the size, borders and shape of the lesions followed by Toluidine blue and Incandescent light examinations. Toluidine blue and Vizilite plus examination methods demonstrated the sensitivity of 100% and specificity of 97.3%. They also demonstrated PPV of 100% and NPV of 75% with reliable accuracy of 97.5%. CONCLUSION: Chemiluminescent light is a stepping stone and has the potential to revolutionize the diagnostic protocol for patients with potentially premalignant lesions. The device can be used as a general oral mucosal examination system and may in particular improve the visualization of potentially premalignant lesions.