Literature DB >> 30191039

Regorafenib and the RESORCE trial: a new second-line option for hepatocellular carcinoma patients.

Jordi Bruix1.   

Abstract

Dr Jordi Bruix* speaks to Laura Dormer, Editorial Director: Dr Jordi Bruix is the Head of the Barcelona Clinic Liver Cancer (BCLC) group at the Hospital Clinic (University of Barcelona, Spain) and Director of the Network for Research in Liver and Digestive Disease (CIBEREHD) in the Spanish Research Institute. His research has changed the diagnosis and treatment of liver cancer. Major highlights include: development of the BCLC staging and treatment; development of diagnostic criteria for hepatocellular carcinoma; identification of the value of portal pressure in predicting prognosis after resection; and acting as principal investigator of the Phase III trials that have shown the benefits of chemoembolization, sorafenib and regorafenib for patients with liver cancer. He has authored the European Assoaciation for the Study of the Liver, American Association for the Study of Liver Diseases and World Gastroenterology Organization Practice Guidelines and the United Network for Organ Sharing hepatocellular carcinoma (HCC) diagnostic criteria.

Entities:  

Keywords:  hepatocellular carcinoma; randomized controlled trial; regorafenib; sorafenib; survival; treatment

Year:  2016        PMID: 30191039      PMCID: PMC6095319          DOI: 10.2217/hep-2016-0007

Source DB:  PubMed          Journal:  Hepat Oncol        ISSN: 2045-0923


  2 in total

Review 1.  Implications of Immunotherapy in Hepatobiliary Tumors.

Authors:  Aline Gottlieb; Jan Best; Ali Canbay
Journal:  Visc Med       Date:  2019-02-08

2.  Sorafenib is associated with a reduced rate of tumour growth and liver function deterioration in HCV-induced hepatocellular carcinoma.

Authors:  Ruwanthi Kolamunnage-Dona; Sarah Berhane; Harry Potts; Edward H Williams; James Tanner; Tobias Janowitz; Matthew Hoare; Philip Johnson
Journal:  J Hepatol       Date:  2021-05-27       Impact factor: 30.083

  2 in total

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