Literature DB >> 30191011

DNA methylation in hepatocellular carcinoma: what is the use?

Jeroen Dekervel1, Jos van Pelt1, Chris Verslype1.   

Abstract

Entities:  

Keywords:  DNA methylation; biomarkers; epigenetics; hepatocellular carcinoma; liver cancer; targeted therapy

Year:  2015        PMID: 30191011      PMCID: PMC6095174          DOI: 10.2217/hep.15.22

Source DB:  PubMed          Journal:  Hepat Oncol        ISSN: 2045-0923


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  22 in total

1.  Chromosomal instability and tumors promoted by DNA hypomethylation.

Authors:  Amir Eden; François Gaudet; Alpana Waghmare; Rudolf Jaenisch
Journal:  Science       Date:  2003-04-18       Impact factor: 47.728

2.  SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity.

Authors:  H Yoshikawa; K Matsubara; G S Qian; P Jackson; J D Groopman; J E Manning; C C Harris; J G Herman
Journal:  Nat Genet       Date:  2001-05       Impact factor: 38.330

Review 3.  Epigenetics in cancer.

Authors:  Manel Esteller
Journal:  N Engl J Med       Date:  2008-03-13       Impact factor: 91.245

4.  Genome-wide methylation analysis and epigenetic unmasking identify tumor suppressor genes in hepatocellular carcinoma.

Authors:  Kate Revill; Tim Wang; Anja Lachenmayer; Kensuke Kojima; Andrew Harrington; Jinyu Li; Yujin Hoshida; Josep M Llovet; Scott Powers
Journal:  Gastroenterology       Date:  2013-09-05       Impact factor: 22.682

Review 5.  Epigenomes as therapeutic targets.

Authors:  Christopher A Hamm; Fabricio F Costa
Journal:  Pharmacol Ther       Date:  2015-03-20       Impact factor: 12.310

6.  Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis.

Authors:  Yasuhiro Yamada; Laurie Jackson-Grusby; Heinz Linhart; Alex Meissner; Amir Eden; Haijiang Lin; Rudolf Jaenisch
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-08       Impact factor: 11.205

Review 7.  TET enzymes, TDG and the dynamics of DNA demethylation.

Authors:  Rahul M Kohli; Yi Zhang
Journal:  Nature       Date:  2013-10-24       Impact factor: 49.962

8.  Aberrant CpG island hypermethylation in dysplastic nodules and early HCC of hepatitis B virus-related human multistep hepatocarcinogenesis.

Authors:  Tae-Hee Um; Haeryoung Kim; Bong-Kyeong Oh; Myoung Soo Kim; Kyung Sik Kim; Guhung Jung; Young Nyun Park
Journal:  J Hepatol       Date:  2010-10-29       Impact factor: 25.083

9.  Concordance of DNA methylation pattern in plasma and tumor DNA of Egyptian hepatocellular carcinoma patients.

Authors:  Priyanka Iyer; Abdel-Rahman Zekri; Chu-Wei Hung; Emily Schiefelbein; Kadry Ismail; Ahmed Hablas; Ibrahim A Seifeldin; Amr S Soliman
Journal:  Exp Mol Pathol       Date:  2009-10-07       Impact factor: 3.362

Review 10.  Hallmarks of cancer: the next generation.

Authors:  Douglas Hanahan; Robert A Weinberg
Journal:  Cell       Date:  2011-03-04       Impact factor: 41.582

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