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Literature DB >> 30191010

The search for precision models clinically relevant to human liver cancer.

Abstract

Entities: Disease Species

Keywords: CRISPR technology; RNA interference; hepatocellular carcinoma; knockout mice; liver cancer; transgenic mice; tumor heterogeneity

Year: 2015 PMID： 30191010 PMCID： PMC6095146 DOI： 10.2217/hep.15.24

Source DB: PubMed Journal: Hepat Oncol ISSN： 2045-0923

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30 in total

1. Trans-ancestry mutational landscape of hepatocellular carcinoma genomes.

Authors: Yasushi Totoki; Kenji Tatsuno; Kyle R Covington; Hiroki Ueda; Chad J Creighton; Mamoru Kato; Shingo Tsuji; Lawrence A Donehower; Betty L Slagle; Hiromi Nakamura; Shogo Yamamoto; Eve Shinbrot; Natsuko Hama; Megan Lehmkuhl; Fumie Hosoda; Yasuhito Arai; Kim Walker; Mahmoud Dahdouli; Kengo Gotoh; Genta Nagae; Marie-Claude Gingras; Donna M Muzny; Hidenori Ojima; Kazuaki Shimada; Yutaka Midorikawa; John A Goss; Ronald Cotton; Akimasa Hayashi; Junji Shibahara; Shumpei Ishikawa; Jacfranz Guiteau; Mariko Tanaka; Tomoko Urushidate; Shoko Ohashi; Naoko Okada; Harsha Doddapaneni; Min Wang; Yiming Zhu; Huyen Dinh; Takuji Okusaka; Norihiro Kokudo; Tomoo Kosuge; Tadatoshi Takayama; Masashi Fukayama; Richard A Gibbs; David A Wheeler; Hiroyuki Aburatani; Tatsuhiro Shibata
Journal: Nat Genet Date: 2014-11-02 Impact factor: 38.330

Review 2. Genome editing. The new frontier of genome engineering with CRISPR-Cas9.

Authors: Jennifer A Doudna; Emmanuelle Charpentier
Journal: Science Date: 2014-11-28 Impact factor: 47.728

Review 3. Interspecies comparison of liver carcinogenesis: implications for cancer risk assessment.

Authors: J W Grisham
Journal: Carcinogenesis Date: 1997-01 Impact factor: 4.944

4. Generation of a humanized mouse model with both human immune system and liver cells to model hepatitis C virus infection and liver immunopathogenesis.

Authors: Moses T Bility; Liguo Zhang; Michael L Washburn; T Anthony Curtis; Grigoriy I Kovalev; Lishan Su
Journal: Nat Protoc Date: 2012-08-09 Impact factor: 13.491

The search for precision models clinically relevant to human liver cancer.

1. Trans-ancestry mutational landscape of hepatocellular carcinoma genomes.

Review 2. Genome editing. The new frontier of genome engineering with CRISPR-Cas9.

Review 3. Interspecies comparison of liver carcinogenesis: implications for cancer risk assessment.

4. Generation of a humanized mouse model with both human immune system and liver cells to model hepatitis C virus infection and liver immunopathogenesis.

Review 5. Genetic Landscape and Biomarkers of Hepatocellular Carcinoma.

6. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults.

Review 7. Current advances in humanized mouse models.

8. A transgenic mouse model of the chronic hepatitis B surface antigen carrier state.

Review 9. Experimental models of hepatocellular carcinoma.

Review 10. Identification of drivers from cancer genome diversity in hepatocellular carcinoma.

1. Depletion of TRRAP Induces p53-Independent Senescence in Liver Cancer by Down-Regulating Mitotic Genes.

2. CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling.