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Literature DB >> 30190867

What are the therapeutic implications of increased collagen expression in melanoma cells treated with vemurafenib?

Abstract

Entities: Chemical Disease

Keywords: BRAFV600E; BRAFWT; MAPK signaling; MEK inhibitors; TGF-β; carcinoma-activated fibroblasts; fibroblasts; tumor microenvironment; vemurafenib/PLX4032

Year: 2016 PMID： 30190867 PMCID： PMC6094651 DOI： 10.2217/mmt.15.36

Source DB: PubMed Journal: Melanoma Manag ISSN： 2045-0885

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20 in total

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Authors: Benjamin Diop-Frimpong; Vikash P Chauhan; Stephen Krane; Yves Boucher; Rakesh K Jain
Journal: Proc Natl Acad Sci U S A Date: 2011-01-31 Impact factor: 11.205

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Authors: Hsueh-Liang Fu; Rajeshwari R Valiathan; Richard Arkwright; Anjum Sohail; Cosmin Mihai; Malika Kumarasiri; Kiran V Mahasenan; Shahriar Mobashery; Paul Huang; Gunjan Agarwal; Rafael Fridman
Journal: J Biol Chem Date: 2013-01-18 Impact factor: 5.157

Review 3. Resistance to BRAF inhibitors: unraveling mechanisms and future treatment options.

Authors: Jessie Villanueva; Adina Vultur; Meenhard Herlyn
Journal: Cancer Res Date: 2011-12-01 Impact factor: 12.701

4. Contact with fibrillar collagen inhibits melanoma cell proliferation by up-regulating p27KIP1.

Authors: P Henriet; Z D Zhong; P C Brooks; K I Weinberg; Y A DeClerck
Journal: Proc Natl Acad Sci U S A Date: 2000-08-29 Impact factor: 11.205

5. The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner.

Authors: Eric W Joseph; Christine A Pratilas; Poulikos I Poulikakos; Madhavi Tadi; Weiqing Wang; Barry S Taylor; Ensar Halilovic; Yogindra Persaud; Feng Xing; Agnes Viale; James Tsai; Paul B Chapman; Gideon Bollag; David B Solit; Neal Rosen
Journal: Proc Natl Acad Sci U S A Date: 2010-07-28 Impact factor: 11.205

6. TGF-β signaling, activated stromal fibroblasts, and cysteine cathepsins B and L drive the invasive growth of human melanoma cells.

Authors: Miao Yin; Johanna Soikkeli; Tiina Jahkola; Susanna Virolainen; Olli Saksela; Erkki Hölttä
Journal: Am J Pathol Date: 2012-10-10 Impact factor: 4.307

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Journal: Int J Cancer Date: 2008-03-01 Impact factor: 7.396