| Literature DB >> 30190833 |
Abstract
Metastatic melanoma is a disease with a historically dismal survival of 6-9 months with treatment. It is considered an incurable disease and resistant to conventional chemotherapy. We have learned much about the role of newer targets in the development of melanoma which has helped us in developing targeted therapy and improving immunotherapy for the treatment of melanoma. These new therapies have a different adverse event profile from conventional chemotherapy. We will define these and their management from the perspective of the oncology pharmacist. We will also discuss the role that the oncology pharmacist can play in optimizing therapy and side effect management in the multidisciplinary team treating patients that have unresectable or metastatic melanoma.Entities:
Keywords: BRAF inhibitors; dabrafenib; immunotherapy; ipilimumab; melanoma; oncology pharmacist; trametinib; vemurafenib
Year: 2015 PMID: 30190833 PMCID: PMC6094589 DOI: 10.2217/mmt.14.33
Source DB: PubMed Journal: Melanoma Manag ISSN: 2045-0885