Literature DB >> 3018928

Early signals in the mitogenic response.

E Rozengurt.   

Abstract

Polypeptide growth factors, regulatory peptides, and a variety of pharmacological agents acting alone or synergistically induce mitogenesis in cultured fibroblasts. The early signals in the membrane, cytosol, and nucleus promoted by these extracellular factors, together with their mitogenic effectiveness, are integrated in a unified hypothesis for the regulation of fibroblast growth.

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Year:  1986        PMID: 3018928     DOI: 10.1126/science.3018928

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  260 in total

1.  Activation of phosphatidylinositol-3 kinase (PI-3K) and extracellular regulated kinases (Erk1/2) is involved in muscarinic receptor-mediated DNA synthesis in neural progenitor cells.

Authors:  B S Li; W Ma; L Zhang; J L Barker; D A Stenger; H C Pant
Journal:  J Neurosci       Date:  2001-03-01       Impact factor: 6.167

2.  Cell volume and rate of proliferation, but not protein expression pattern, distinguish pup/intimal smooth muscle cells from subcultured adult smooth muscle cells.

Authors:  E McKilligin; D J Grainger
Journal:  Cell Prolif       Date:  2001-10       Impact factor: 6.831

3.  PKC isoenzyme expression and cellular responses to phorbol ester in JEG-3 choriocarcinoma cells.

Authors:  A M Bamberger; C M Bamberger; M Wald; K Jensen; H M Schulte
Journal:  Endocrine       Date:  1997-04       Impact factor: 3.633

4.  Epithelins 1 and 2: isolation and characterization of two cysteine-rich growth-modulating proteins.

Authors:  M Shoyab; V L McDonald; C Byles; G J Todaro; G D Plowman
Journal:  Proc Natl Acad Sci U S A       Date:  1990-10       Impact factor: 11.205

5.  Mutated alpha subunit of the Gq protein induces malignant transformation in NIH 3T3 cells.

Authors:  G Kalinec; A J Nazarali; S Hermouet; N Xu; J S Gutkind
Journal:  Mol Cell Biol       Date:  1992-10       Impact factor: 4.272

6.  Targetable T-type Calcium Channels Drive Glioblastoma.

Authors:  Ying Zhang; Nichola Cruickshanks; Fang Yuan; Baomin Wang; Mary Pahuski; Julia Wulfkuhle; Isela Gallagher; Alexander F Koeppel; Sarah Hatef; Christopher Papanicolas; Jeongwu Lee; Eli E Bar; David Schiff; Stephen D Turner; Emanuel F Petricoin; Lloyd S Gray; Roger Abounader
Journal:  Cancer Res       Date:  2017-05-16       Impact factor: 12.701

7.  Alpha interferon and gamma interferon stimulate transcription of a single gene through different signal transduction pathways.

Authors:  D J Lew; T Decker; J E Darnell
Journal:  Mol Cell Biol       Date:  1989-12       Impact factor: 4.272

8.  Transmodulation of the epidermal-growth-factor receptor in permeabilized 3T3 cells.

Authors:  F Walker; A W Burgess
Journal:  Biochem J       Date:  1988-11-15       Impact factor: 3.857

9.  Interleukin-3-stimulated haemopoietic stem cell proliferation. Evidence for activation of protein kinase C and Na+/H+ exchange without inositol lipid hydrolysis.

Authors:  A D Whetton; S J Vallance; P N Monk; E J Cragoe; T M Dexter; C M Heyworth
Journal:  Biochem J       Date:  1988-12-01       Impact factor: 3.857

10.  Single channel study of a Ca(2+)-activated K+ current associated with ras-induced cell transformation.

Authors:  Y Huang; S G Rane
Journal:  J Physiol       Date:  1993-02       Impact factor: 5.182

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