Literature DB >> 30189223

Preparation, properties and challenges of the microneedles-based insulin delivery system.

Xiang Chen1, Li Wang2, Haojie Yu1, Chengjiang Li3, Jingyi Feng3, Fazal Haq1, Amin Khan1, Rizwan Ullah Khan1.   

Abstract

Microneedle technology relates to pharmacy, polymer chemistry and micromachining. Microneedle can effectively deliver insulin into systemic circulation across the skin. This process does not affect the activity of insulin. Compared to subcutaneous injection, microneedles cause less pain for their special structure. This review thoroughly discusses the preparation technologies of the microneedles-based insulin delivery system including solid, hollow, dissolving, phase transition, glucose-responsive microneedle patches. In the meantime, the properties, challenges and clinical/commercial status of the microneedles-based insulin delivery system are also discussed in this review.
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Diabetes; Glucose-responsive microneedle; Hydrogel; Insulin; Microneedle fabrication; Phase transition microneedle; Skin

Mesh：

Substances：

Year:  2018        PMID： 30189223     DOI： 10.1016/j.jconrel.2018.08.042

Source DB:  PubMed          Journal:  J Control Release        ISSN： 0168-3659            Impact factor:   9.776


  12 in total

1.  Antibiofilm Efficacy of the Pseudomonas aeruginosa Pbunavirus vB_PaeM-SMS29 Loaded onto Dissolving Polyvinyl Alcohol Microneedles.

Authors:  Sanna Sillankorva; Liliana Pires; Lorenzo M Pastrana; Manuel Bañobre-López
Journal:  Viruses       Date:  2022-05-05       Impact factor: 5.818

Review 2.  Beneath the Skin: A Review of Current Trends and Future Prospects of Transdermal Drug Delivery Systems.

Authors:  Ahlam Zaid Alkilani; Jehad Nasereddin; Rania Hamed; Sukaina Nimrawi; Ghaid Hussein; Hadeel Abo-Zour; Ryan F Donnelly
Journal:  Pharmaceutics       Date:  2022-05-28       Impact factor: 6.525

3.  A Porous Reservoir-Backed Boronate Gel Microneedle for Efficient Skin Penetration and Sustained Glucose-Responsive Insulin Delivery.

Authors:  Siyuan Chen; Takuya Miyazaki; Michiko Itoh; Hiroko Matsumoto; Yuki Moro-Oka; Miyako Tanaka; Yuji Miyahara; Takayoshi Suganami; Akira Matsumoto
Journal:  Gels       Date:  2022-01-24

Review 4.  Design and development of insulin microneedles for diabetes treatment.

Authors:  Qida Zong; Ranran Guo; Naijun Dong; Guixia Ling; Peng Zhang
Journal:  Drug Deliv Transl Res       Date:  2021-04-13       Impact factor: 4.617

Review 5.  Topical and Transdermal Drug Delivery: From Simple Potions to Smart Technologies.

Authors:  Heather A E Benson; Jeffrey E Grice; Yousuf Mohammed; Sarika Namjoshi; Michael S Roberts
Journal:  Curr Drug Deliv       Date:  2019       Impact factor: 2.565

Review 6.  Delivery of Insulin via Skin Route for the Management of Diabetes Mellitus: Approaches for Breaching the Obstacles.

Authors:  Abdul Ahad; Mohammad Raish; Yousef A Bin Jardan; Abdullah M Al-Mohizea; Fahad I Al-Jenoobi
Journal:  Pharmaceutics       Date:  2021-01-14       Impact factor: 6.321

Review 7.  Microneedle-based insulin transdermal delivery system: current status and translation challenges.

Authors:  Jing Zhao; Genying Xu; Xin Yao; Huirui Zhou; Boyang Lyu; Shuangshuang Pei; Ping Wen
Journal:  Drug Deliv Transl Res       Date:  2021-10-20       Impact factor: 5.671

Review 8.  The Role of Regulatory T Cells in Epicutaneous Immunotherapy for Food Allergy.

Authors:  Guirong Liu; Manman Liu; Junjuan Wang; Yao Mou; Huilian Che
Journal:  Front Immunol       Date:  2021-07-08       Impact factor: 7.561

9.  Rapid quantification of insulin degludec by immunopurification combined with liquid chromatography high-resolution mass spectrometry.

Authors:  Gemma Reverter-Branchat; Michael Groessl; Christos T Nakas; Jean-Christophe Prost; Kwasi Antwi; Eric E Niederkofler; Lia Bally
Journal:  Anal Bioanal Chem       Date:  2020-10-02       Impact factor: 4.142

10.  Enhancement strategies for transdermal drug delivery systems: current trends and applications.

Authors:  Delly Ramadon; Maeliosa T C McCrudden; Aaron J Courtenay; Ryan F Donnelly
Journal:  Drug Deliv Transl Res       Date:  2021-01-20       Impact factor: 4.617
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