Literature DB >> 30188572

GENIPSO: a French prospective study assessing instantaneous prevalence, clinical features and impact on quality of life of genital psoriasis among patients consulting for psoriasis.

M Larsabal1, S Ly1,2,3, E Sbidian3,4,5, M Moyal-Barracco2,6, J-N Dauendorffer2,3,7, N Dupin6,8, M A Richard3,9, O Chosidow3,4,5,8, M Beylot-Barry1,3.   

Abstract

BACKGROUND: Genital psoriasis is often under-recognized.
OBJECTIVES: To assess the instantaneous prevalence of genital psoriasis and describe its clinical features, association with a particular subtype of psoriasis and its impact on general and sexual quality of life (QoL).
METHODS: GENIPSO is a prospective study conducted by private and hospital-based dermatologists. This study featured the consecutive inclusion of patients consulting for extragenital psoriasis. The clinical features of psoriasis and genital psoriasis were recorded and QoL and sexual health questionnaires were distributed to patients.
RESULTS: Overall, 335 of 776 patients (43·2%) included in the study had genital involvement. All were aware that they had genital lesions but only 135 patients (40%) declared that they had been previously examined. Genital lesions were associated with male sex, severity of psoriasis, age of onset > 20 years, inverse psoriasis and involvement of scalp, nail and external auditory canal, but were not associated with obesity, psoriatic arthritis and active sex life. Itching was the main symptom. Genital psoriasis was associated with impairment of QoL and sexual health according to the Dermatology Life Quality Index and the Female Sexual Function Index.
CONCLUSIONS: Genital psoriasis has a high prevalence in patients consulting for extragenital psoriasis, which affects QoL, and should be taken into account by dermatologists in order to optimize global care.
© 2018 British Association of Dermatologists.

Entities:  

Mesh:

Year:  2018        PMID: 30188572     DOI: 10.1111/bjd.17147

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  14 in total

1.  The Skin May Clear But the Arthritis Won't Disappear: Focusing on Concomitant and New-Onset Psoriatic Arthritis in a Daily Practice Cohort of Psoriasis Patients on Biologic Therapy.

Authors:  Marloes E van Muijen; Tamara W van Hal; Hans M M Groenewoud; Juul M P A van den Reek; Elke M G J de Jong
Journal:  Psoriasis (Auckl)       Date:  2020-10-05

2.  Therapeutic Inertia in the Management of Moderate-to-Severe Plaque Psoriasis in Adolescents.

Authors:  Audrey Melin; Jean-François Sei; Florence Corgibet; Cristèle Nicolas; Rémi Maghia; Bruno Halioua; Alain Beauchet; Emmanuel Mahé
Journal:  Acta Derm Venereol       Date:  2021-06-22       Impact factor: 3.875

3.  Epidemiology of psoriasis in hard-to-treat body locations: data from the Danish skin cohort.

Authors:  Alexander Egeberg; Kyoungah See; Alyssa Garrelts; Russel Burge
Journal:  BMC Dermatol       Date:  2020-05-20

4.  Sex-related impairment and patient needs/benefits in anogenital psoriasis: Difficult-to-communicate topics and their impact on patient-centred care.

Authors:  Neuza da Silva; Matthias Augustin; Anna Langenbruch; Ulrich Mrowietz; Kristian Reich; Diamant Thaçi; Wolf-Henning Boehncke; Natalia Kirsten; Alexandra Danckworth; Rachel Sommer
Journal:  PLoS One       Date:  2020-07-01       Impact factor: 3.240

5.  Ixekizumab improves secondary lesional signs, pain and sexual health in patients with moderate-to-severe genital psoriasis.

Authors:  J F Merola; P-D Ghislain; J N Dauendorffer; A Potts Bleakman; A J M Brnabic; R Burge; E Riedl
Journal:  J Eur Acad Dermatol Venereol       Date:  2020-02-05       Impact factor: 6.166

6.  Psychometric validation of a patient-reported outcome questionnaire (Qualipsosex) assessing the impact of psoriasis and psoriatic arthritis on patient perception of sexuality.

Authors:  Eric Lespessailles; Emmanuel Mahé; Ziad Reguiai; Edouard Begon; François Maccari; Nathalie Beneton; Guillaume Chaby; Carole Rosenberg; Emmanuelle Dernis; Fabienne Roux; Isabelle Henry-Desailly; Bénédicte Charles; Cyril Ferdynus; Marc Marty; Eric Esteve
Journal:  Medicine (Baltimore)       Date:  2021-01-08       Impact factor: 1.817

Review 7.  Optimal Management of Plaque Psoriasis in Adolescents: Current Perspectives.

Authors:  Emmanuel Mahé
Journal:  Psoriasis (Auckl)       Date:  2020-11-27

Review 8.  "Autoinflammatory psoriasis"-genetics and biology of pustular psoriasis.

Authors:  Ranjitha Uppala; Lam C Tsoi; Paul W Harms; Bo Wang; Allison C Billi; Emanual Maverakis; J Michelle Kahlenberg; Nicole L Ward; Johann E Gudjonsson
Journal:  Cell Mol Immunol       Date:  2020-08-19       Impact factor: 11.530

9.  Ixekizumab Results in Persistent Clinical Improvement in Moderate-to-Severe Genital Psoriasis During a 52 Week, Randomized, Placebo-Controlled, Phase 3 Clinical Trial.

Authors:  Lyn Guenther; Alison Potts Bleakman; Jamie Weisman; Yves Poulin; Lynda Spelman; Russel Burge; Janelle Erickson; Kristin Todd; Clinton C Bertram; Caitriona Ryan
Journal:  Acta Derm Venereol       Date:  2020-01-07       Impact factor: 3.875

10.  Genital Psoriasis and Associated Factors of Sexual Avoidance - A People-centered Cross-sectional Study in Germany.

Authors:  Maximilian Christian Schielein; Linda Tizek; Barbara Schuster; Stefanie Ziehfreund; Tilo Biedermann; Alexander Zink
Journal:  Acta Derm Venereol       Date:  2020-05-28       Impact factor: 3.875

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