Literature DB >> 30188529

Small molecules get the message.

Justin Petrone, Laura DeFrancesco.   

Abstract

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Year:  2018        PMID： 30188529     DOI： 10.1038/nbt.4241

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  8 in total

1.  SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Authors:  James Palacino; Susanne E Swalley; Cheng Song; Atwood K Cheung; Lei Shu; Xiaolu Zhang; Mailin Van Hoosear; Youngah Shin; Donovan N Chin; Caroline Gubser Keller; Martin Beibel; Nicole A Renaud; Thomas M Smith; Michael Salcius; Xiaoying Shi; Marc Hild; Rebecca Servais; Monish Jain; Lin Deng; Caroline Bullock; Michael McLellan; Sven Schuierer; Leo Murphy; Marcel J J Blommers; Cecile Blaustein; Frada Berenshteyn; Arnaud Lacoste; Jason R Thomas; Guglielmo Roma; Gregory A Michaud; Brian S Tseng; Jeffery A Porter; Vic E Myer; John A Tallarico; Lawrence G Hamann; Daniel Curtis; Mark C Fishman; William F Dietrich; Natalie A Dales; Rajeev Sivasankaran
Journal:  Nat Chem Biol       Date:  2015-06-01       Impact factor: 15.040

2.  Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry.

Authors:  Noreen F Rizvi; John A Howe; Ali Nahvi; Daniel J Klein; Thierry O Fischmann; Hai-Young Kim; Mark A McCoy; Scott S Walker; Alan Hruza; Matthew P Richards; Chad Chamberlin; Peter Saradjian; Margaret T Butko; Gabriel Mercado; Julja Burchard; Corey Strickland; Peter J Dandliker; Graham F Smith; Elliott B Nickbarg
Journal:  ACS Chem Biol       Date:  2018-02-14       Impact factor: 5.100

3.  Pervasive Regulatory Functions of mRNA Structure Revealed by High-Resolution SHAPE Probing.

Authors:  Anthony M Mustoe; Steven Busan; Greggory M Rice; Christine E Hajdin; Brant K Peterson; Vera M Ruda; Neil Kubica; Razvan Nutiu; Jeremy L Baryza; Kevin M Weeks
Journal:  Cell       Date:  2018-03-15       Impact factor: 41.582

4.  Precise small-molecule recognition of a toxic CUG RNA repeat expansion.

Authors:  Suzanne G Rzuczek; Lesley A Colgan; Yoshio Nakai; Michael D Cameron; Denis Furling; Ryohei Yasuda; Matthew D Disney
Journal:  Nat Chem Biol       Date:  2016-12-12       Impact factor: 15.040

5.  PTC124 targets genetic disorders caused by nonsense mutations.

Authors:  Ellen M Welch; Elisabeth R Barton; Jin Zhuo; Yuki Tomizawa; Westley J Friesen; Panayiota Trifillis; Sergey Paushkin; Meenal Patel; Christopher R Trotta; Seongwoo Hwang; Richard G Wilde; Gary Karp; James Takasugi; Guangming Chen; Stephen Jones; Hongyu Ren; Young-Choon Moon; Donald Corson; Anthony A Turpoff; Jeffrey A Campbell; M Morgan Conn; Atiyya Khan; Neil G Almstead; Jean Hedrick; Anna Mollin; Nicole Risher; Marla Weetall; Shirley Yeh; Arthur A Branstrom; Joseph M Colacino; John Babiak; William D Ju; Samit Hirawat; Valerie J Northcutt; Langdon L Miller; Phyllis Spatrick; Feng He; Masataka Kawana; Huisheng Feng; Allan Jacobson; Stuart W Peltz; H Lee Sweeney
Journal:  Nature       Date:  2007-04-22       Impact factor: 49.962

6.  H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers.

Authors:  Michael Seiler; Akihide Yoshimi; Rachel Darman; Betty Chan; Gregg Keaney; Michael Thomas; Anant A Agrawal; Benjamin Caleb; Alfredo Csibi; Eckley Sean; Peter Fekkes; Craig Karr; Virginia Klimek; George Lai; Linda Lee; Pavan Kumar; Stanley Chun-Wei Lee; Xiang Liu; Crystal Mackenzie; Carol Meeske; Yoshiharu Mizui; Eric Padron; Eunice Park; Ermira Pazolli; Shouyong Peng; Sudeep Prajapati; Justin Taylor; Teng Teng; John Wang; Markus Warmuth; Huilan Yao; Lihua Yu; Ping Zhu; Omar Abdel-Wahab; Peter G Smith; Silvia Buonamici
Journal:  Nat Med       Date:  2018-02-19       Impact factor: 53.440

7.  Mechanistic studies of a small-molecule modulator of SMN2 splicing.

Authors:  Jingxin Wang; Peter G Schultz; Kristen A Johnson
Journal:  Proc Natl Acad Sci U S A       Date:  2018-04-30       Impact factor: 11.205

8.  Identifying the preferred RNA motifs and chemotypes that interact by probing millions of combinations.

Authors:  Tuan Tran; Matthew D Disney
Journal:  Nat Commun       Date:  2012       Impact factor: 14.919
  8 in total
  7 in total

1.  Small molecule-RNA targeting: starting with the fundamentals.

Authors:  Amanda E Hargrove
Journal:  Chem Commun (Camb)       Date:  2020-11-26       Impact factor: 6.222

2.  Visualizing the functional 3D shape and topography of long noncoding RNAs by single-particle atomic force microscopy and in-solution hydrodynamic techniques.

Authors:  Tina Uroda; Isabel Chillón; Paolo Annibale; Jean-Marie Teulon; Ombeline Pessey; Manikandan Karuppasamy; Jean-Luc Pellequer; Marco Marcia
Journal:  Nat Protoc       Date:  2020-05-25       Impact factor: 13.491

3.  SILCS-RNA: Toward a Structure-Based Drug Design Approach for Targeting RNAs with Small Molecules.

Authors:  Abhishek A Kognole; Anthony Hazel; Alexander D MacKerell
Journal:  J Chem Theory Comput       Date:  2022-08-01       Impact factor: 6.578

4.  Efficient NMR Screening Approach to Discover Small Molecule Fragments Binding Structured RNA.

Authors:  Matthew D Shortridge; Gabriele Varani
Journal:  ACS Med Chem Lett       Date:  2021-07-13       Impact factor: 4.632

Review 5.  RNA-Targeted Therapies and High-Throughput Screening Methods.

Authors:  Siran Zhu; Saul Rooney; Gracjan Michlewski
Journal:  Int J Mol Sci       Date:  2020-04-23       Impact factor: 5.923

6.  Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions.

Authors:  Joy S Xiang; Jasmine R Mueller; En-Ching Luo; Brian A Yee; Danielle Schafer; Jonathan C Schmok; Frederick E Tan; Katherine Rothamel; Rachael N McVicar; Elizabeth M Kwong; Krysten L Jones; Hsuan-Lin Her; Chun-Yuan Chen; Anthony Q Vu; Wenhao Jin; Samuel S Park; Phuong Le; Kristopher W Brannan; Eric R Kofman; Yanhua Li; Alexandra T Tankka; Kevin D Dong; Yan Song; Aaron F Carlin; Eric L Van Nostrand; Sandra L Leibel; Gene W Yeo
Journal:  bioRxiv       Date:  2022-02-23

7.  Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions.

Authors:  Gene Yeo; Joy Xiang; Jasmine Mueller; En-Ching Luo; Brian Yee; Danielle Schafer; Jonathan Schmok; Frederick Tan; Katherine Rothamel; Rachael McVicar; Elizabeth Kwong; Ben Croker; Krysten Jones; Hsuan-Lin Her; Chun-Yuan Chen; Anthony Vu; Wenhao Jin; Samuel Park; Phuong Le; Kristopher Brennan; Eric Kofman; Yanhua Li; Alexandra Tankka; Kevin Dong; Yan Song; Alex Clark; Aaron Carlin; Eric Van Nostrand; Sandra Leibel
Journal:  Res Sq       Date:  2022-03-17
  7 in total

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