Literature DB >> 3018579

Bovine papillomavirus genome elicits skin tumours in transgenic mice.

M Lacey, S Alpert, D Hanahan.   

Abstract

Transmission of the bovine papillomavirus-1 (BPV-1) genome through the mouse germ line results in the heritable formation of fibropapillomas of the skin, a tissue-specific phenotype analogous to that observed in natural BPV-1 infection of cattle. Oncogenesis is slow, with tumours first arising at 8-9 months of age, usually in areas prone to wounding. Extrachromosomal BPV-1 DNA is detected in all tumours, whereas normal tissues show only integrated DNA.

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Year:  1986        PMID： 3018579     DOI： 10.1038/322609a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  30 in total

1.  Retroviral transduction of the human c-Ha-ras-1 oncogene into midgestation mouse embryos promotes rapid epithelial hyperplasia.

Authors:  S J Compere; P A Baldacci; A H Sharpe; R Jaenisch
Journal:  Mol Cell Biol       Date:  1989-01       Impact factor: 4.272

2.  Use of a rapid, efficient inoculation method to induce papillomas by cottontail rabbit papillomavirus DNA shows that the E7 gene is required.

Authors:  J L Brandsma; Z H Yang; S W Barthold; E A Johnson
Journal:  Proc Natl Acad Sci U S A       Date:  1991-06-01       Impact factor: 11.205

Review 3.  Transgenic regulation in laboratory animals.

Authors:  S Rusconi
Journal:  Experientia       Date:  1991-09-15

Review 4.  Angiogenesis in transgenic models of multistep carcinogenesis.

Authors:  M G D' Angelo; T Afanasieva; A Aguzzi
Journal:  J Neurooncol       Date:  2000 Oct-Nov       Impact factor: 4.130

5.  Loss of p16INK4a results in increased glucocorticoid receptor activity during fibrosarcoma development.

Authors:  Ramon Roca; Robert M Kypta; Maria d M Vivanco
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-06       Impact factor: 11.205

Review 6.  Germ-line transformation of mice.

Authors:  R D Palmiter; R L Brinster
Journal:  Annu Rev Genet       Date:  1986       Impact factor: 16.830

7.  Targeted expression of the E6 and E7 oncogenes of human papillomavirus type 16 in the epidermis of transgenic mice elicits generalized epidermal hyperplasia involving autocrine factors.

Authors:  P Auewarakul; L Gissmann; A Cid-Arregui
Journal:  Mol Cell Biol       Date:  1994-12       Impact factor: 4.272

8.  Reactivation of proliferin gene expression is associated with increased angiogenesis in a cell culture model of fibrosarcoma tumor progression.

Authors:  D J Toft; S B Rosenberg; G Bergers; O Volpert; D I Linzer
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-23       Impact factor: 11.205

9.  Latent infection induced with cottontail rabbit papillomavirus. A model for human papillomavirus latency.

Authors:  C A Amella; L A Lofgren; A M Ronn; M Nouri; M J Shikowitz; B M Steinberg
Journal:  Am J Pathol       Date:  1994-06       Impact factor: 4.307

10.  Epidermal cancer associated with expression of human papillomavirus type 16 E6 and E7 oncogenes in the skin of transgenic mice.

Authors:  P F Lambert; H Pan; H C Pitot; A Liem; M Jackson; A E Griep
Journal:  Proc Natl Acad Sci U S A       Date:  1993-06-15       Impact factor: 11.205
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