Literature DB >> 30183247

Decoration of Cisplatin on 2D Metal-Organic Frameworks for Enhanced Anticancer Effects through Highly Increased Reactive Oxygen Species Generation.

Yaojia Li1, Zhiguo Gao1, Fanghui Chen1, Chaoqun You1, Hongshuai Wu1, Kai Sun1, Peijing An1, Kaiwu Cheng1, Chen Sun1, Xiaoli Zhu2, Baiwang Sun1.   

Abstract

Herein, a biocompatible 2D metal-organic frameworks (Cu-TCPP(Fe)) based on TCPP(M) (TCPP = tetrakis (4-carboxyphenyl) porphyrin, M = Fe) and copper ion were synthesized as a novel drug carrier. Sequentially, the cisplatin was loaded on the merge of carboxyl-rich Cu-TCPP(Fe) through forming favorable carboxyl-drug interactions. The prepared Pt/Cu-TCPP(Fe) showed highly enhanced cytotoxicity than that of free cisplatin in human pulmonary carcinoma A549 cells, whereas inverse inhibitory effects were observed in human normal BEAS-2B cells. Further, the mechanism of action about the desirable results was also elaborated. Our study highlighted the potential synergies between the nanocarrier and the anticancer drugs.

Entities:  

Keywords:  Fenton reaction; cisplatin; metal−organic frameworks; nanocarrier; reactive oxygen species

Year:  2018        PMID： 30183247     DOI： 10.1021/acsami.8b12800

Source DB:  PubMed          Journal:  ACS Appl Mater Interfaces        ISSN： 1944-8244            Impact factor:   9.229


  8 in total

1.  Unveiling the interplay between homogeneous and heterogeneous catalytic mechanisms in copper-iron nanoparticles working under chemically relevant tumour conditions.

Authors:  Javier Bonet-Aleta; Miguel Encinas-Gimenez; Esteban Urriolabeitia; Pilar Martin-Duque; Jose L Hueso; Jesus Santamaria
Journal:  Chem Sci       Date:  2022-06-08       Impact factor: 9.969

2.  Core-Shell Imidazoline-Functionalized Mesoporous Silica Superparamagnetic Hybrid Nanoparticles as a Potential Theranostic Agent for Controlled Delivery of Platinum(II) Compound.

Authors:  Mehdi Abedi; Samira Sadat Abolmaali; Mozhgan Abedanzadeh; Fatemeh Farjadian; Soliman Mohammadi Samani; Ali Mohammad Tamaddon
Journal:  Int J Nanomedicine       Date:  2020-04-20

Review 3.  Recent Advances in Nanoscale Metal-Organic Frameworks Towards Cancer Cell Cytotoxicity: An Overview.

Authors:  Pierre D Harvey; Jessica Plé
Journal:  J Inorg Organomet Polym Mater       Date:  2021-05-12       Impact factor: 3.518

4.  Cetuximab-modified silica nanoparticle loaded with ICG for tumor-targeted combinational therapy of breast cancer.

Authors:  Xiaoxue Zhang; Yinyan Li; Minjie Wei; Chang Liu; Tao Yu; Jun Yang
Journal:  Drug Deliv       Date:  2019-12       Impact factor: 6.419

Review 5.  Porphyrin-Based Metal-Organic Frameworks for Biomedical Applications.

Authors:  Jiajie Chen; Yufang Zhu; Stefan Kaskel
Journal:  Angew Chem Int Ed Engl       Date:  2020-10-12       Impact factor: 15.336

Review 6.  Fenton/Fenton-like metal-based nanomaterials combine with oxidase for synergistic tumor therapy.

Authors:  Wei Cao; Mengyao Jin; Kang Yang; Bo Chen; Maoming Xiong; Xiang Li; Guodong Cao
Journal:  J Nanobiotechnology       Date:  2021-10-16       Impact factor: 10.435

7.  Cu2O nanoparticles anchored on carbon for the efficient removal of propofol from operating room wastewater via peroxymonosulfate activation: efficiency, mechanism, and pathway.

Authors:  Yujie Tang; Shiyin Zhao; Zemin Peng; Zhen Li; Liang Chen; Pei Gan
Journal:  RSC Adv       Date:  2021-06-14       Impact factor: 4.036

8.  A historical perspective on porphyrin-based metal-organic frameworks and their applications.

Authors:  Xuan Zhang; Megan C Wasson; Mohsen Shayan; Ellan K Berdichevsky; Joseph Ricardo-Noordberg; Zujhar Singh; Edgar K Papazyan; Anthony J Castro; Paola Marino; Zvart Ajoyan; Zhijie Chen; Timur Islamoglu; Ashlee J Howarth; Yangyang Liu; Marek B Majewski; Michael J Katz; Joseph E Mondloch; Omar K Farha
Journal:  Coord Chem Rev       Date:  2020-10-21       Impact factor: 22.315
  8 in total

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