| Literature DB >> 3018052 |
R Rubenstein, H H Roenigk, S J Stegman, C W Hanke.
Abstract
Six patients underwent dermabrasion while on or having recently completed isotretinoin (Accutane) therapy. All patients developed keloids in atypical locations; the keloids eventually responded to topical or intralesional steroid therapy. Retinoids have a modulatory effect on connective tissue metabolism, including suppression of collagenase, which may enhance keloid formation. Dermabrasion should be delayed in those patients taking or recently on isotretinoin therapy.Entities:
Mesh：
Substances：
Year: 1986 PMID： 3018052 DOI： 10.1016/s0190-9622(86)70167-9
Source DB: PubMed Journal: J Am Acad Dermatol ISSN： 0190-9622 Impact factor: 11.527