Literature DB >> 30179055

A successful multidisciplinary approach for treatment and for preserving the reproductive potential in a rare case of acute lymphocytic leukemia during pregnancy.

Mahmoud Salama1,2, Evgenia Isachenko1, Sebastian Ludwig1, Thomas Einzmann1, Gohar Rahimi1, Peter Mallmann1, Vladimir Isachenko1.   

Abstract

Leukemia in pregnancy is a rare condition with the prevalence of 1 in 75,000-100,000 pregnancies. In this case report, we present a successful multidisciplinary management strategy for treatment and for preserving the reproductive potential in a rare case of acute lymphocytic leukemia (ALL) during pregnancy. Several complex challenges existed and necessitated a multidisciplinary approach with strong coordination and collaboration between oncologists, gynecologists, reproductive cryobiologists, obstetricians, and neonatologists in order to improve the maternal and fetal outcome. Pregnancy in the second trimester is neither a contraindication for ALL treatment nor for emergency fertility preservation via ovarian tissue extraction and further cryopreservation.

Entities:  

Keywords:  Leukemia; artificial ovary; autotransplantation; oncofertility; ovarian tissue cryopreservation; pregnancy

Mesh:

Substances:

Year:  2018        PMID: 30179055     DOI: 10.1080/09513590.2018.1498833

Source DB:  PubMed          Journal:  Gynecol Endocrinol        ISSN: 0951-3590            Impact factor:   2.260


  2 in total

1.  Preserving fertility in female patients with hematological malignancies: the key points.

Authors:  Mahmoud Salama; Antoinette Anazodo; Teresa K Woodruff
Journal:  Expert Rev Hematol       Date:  2019-05-06       Impact factor: 2.929

2.  Cryopreservation and Transplantation of Laboratory Rodent Ovarian Tissue for Genome Banking and Biomedical Research.

Authors:  Yuksel Agca; Cansu Agca
Journal:  Methods Mol Biol       Date:  2021
  2 in total

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