Amna Afzal Saeed1, Quratulain Riaz2, Nasir Ud Din3, Sadaf Altaf4. 1. Medical College, Aga Khan University, Karachi, Pakistan. 2. Department of Pediatric Oncology, Aga Khan University Hospital, Karachi, Pakistan. 3. Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan. 4. Department of Pediatric Oncology, Aga Khan University Hospital, Karachi, Pakistan. sadaf.altaf@aku.edu.
Abstract
INTRODUCTION: Primitive myxoid mesenchymal tumor of infancy (PMMTI) is a recently diagnosed entity, with only a handful of cases reported to date. CASE DESCRIPTION: Herein, we present the occurrence of this tumor in a 2-year-old boy, initially diagnosed as primitive neuroectodermal tumor of the extremity and treated with chemotherapy and surgical resection. He later presented with a cerebellar lesion, and biopsy was consistent with PMMTI. CONCLUSION: While there have been previous cases of PMMTI reported with loco-regional metastatic spread, to our knowledge, there is no known incidence of distant metastasis with involvement of the central nervous system, which makes this case the first of its kind.
INTRODUCTION: Primitive myxoid mesenchymal tumor of infancy (PMMTI) is a recently diagnosed entity, with only a handful of cases reported to date. CASE DESCRIPTION: Herein, we present the occurrence of this tumor in a 2-year-old boy, initially diagnosed as primitive neuroectodermal tumor of the extremity and treated with chemotherapy and surgical resection. He later presented with a cerebellar lesion, and biopsy was consistent with PMMTI. CONCLUSION: While there have been previous cases of PMMTI reported with loco-regional metastatic spread, to our knowledge, there is no known incidence of distant metastasis with involvement of the central nervous system, which makes this case the first of its kind.
Entities:
Keywords:
Brain involvement; Metastasis; Primitive myxoid mesenchymal tumor of infancy
Authors: Stuart L Cramer; Rong Li; Siraj Ali; Julie A Bradley; Hee K Kim; Joseph G Pressey Journal: J Natl Compr Canc Netw Date: 2017-07 Impact factor: 11.908