Literature DB >> 30177136

Evaluation of the Safety and Clinical Efficacy of Allogeneic Bone Grafts in the Reconstruction of the Maxilla and Mandible.

Z Stopa1, M Siewert-Gutowska2, K Abed1, D Szubińska-Lelonkiewicz3, A Kamiński4, P Fiedor5.   

Abstract

INTRODUCTION: Loss of teeth caused by inflammatory processes or trauma is one of the causes of bone atrophy of the maxilla alveolar process and the alveolar part of the mandible. Often, restoring these deficiencies with dental implants requires additional reconstructive procedures. Methods using autogenous, allogeneic, xenogeneic, or synthetic bone grafts are commonly used.
MATERIALS AND METHODS: Patients who had bone atrophy of the maxilla or mandible were qualified for deep-frozen transplantation, radiation-sterilized allogeneic bone from the Bank of Tissues in the form of cortico-spongy bone blocks and spongy bone granules. Bone blocks were stabilized with titanium screws, and the free spaces were additionally supplemented with chips from autogenous bone and covered with allogeneic pericardial transplants and platelet-rich fibrin (PRF). Four months after the bone reconstruction, titanium implants were placed, and then after the osseointegration period prosthetic restoration was performed. Clinical safety and efficacy were determined by analyzing the quantity and quality of the reconstructed bone tissue and the degree of resorption was assessed.
RESULTS: The surgical procedures performed confirmed the safety and efficacy of biological material in the reconstruction of the jaw. In two cases, the treatment was not effective and the transplant was removed. In the remaining cases, titanium implants were successfully placed and loaded with prosthetic works. DISCUSSION: Implanting deeply frozen, radiation-sterilized bone is a safe and effective surgical procedure. As an appropriate technique for fixing the allogeneic bone block, additional use of autogenous bone chips and PRF allows one to obtain a good, long-lasting clinical result.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 30177136     DOI: 10.1016/j.transproceed.2018.02.122

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


  5 in total

Review 1.  Clinical Reference Strategy for the Selection of Treatment Materials for Maxillofacial Bone Transplantation: A Systematic Review and Network Meta-Analysis.

Authors:  Shuxin Zhang; Xinyi Zhang; Yanli Li; Xuran Mao; Rui Liu; Yanxin Qi; Eui-Seok Lee; Heng Bo Jiang
Journal:  Tissue Eng Regen Med       Date:  2022-05-09       Impact factor: 4.451

Review 2.  Small Molecules Enhance Scaffold-Based Bone Grafts via Purinergic Receptor Signaling in Stem Cells.

Authors:  Patrick Frank Ottensmeyer; Markus Witzler; Margit Schulze; Edda Tobiasch
Journal:  Int J Mol Sci       Date:  2018-11-14       Impact factor: 5.923

3.  A comparative study of autogenous, allograft and artificial bone substitutes on bone regeneration and immunotoxicity in rat femur defect model.

Authors:  Wen Zou; Xing Li; Na Li; Tianwei Guo; Yongfu Cai; Xiaoqin Yang; Jie Liang; Yong Sun; Yujiang Fan
Journal:  Regen Biomater       Date:  2020-09-30

4.  Collagen-Based Matrices for Osteoconduction: A Preclinical In Vivo Study.

Authors:  Hiroki Katagiri; Yacine El Tawil; Niklaus P Lang; Jean-Claude Imber; Anton Sculean; Masako Fujioka-Kobayashi; Nikola Saulacic
Journal:  Biomedicines       Date:  2021-02-02

5.  Bioactivating a bone substitute accelerates graft incorporation in a murine model of vertical ridge augmentation.

Authors:  Jinlong Chen; Xue Yuan; Zhijun Li; Daniel J Bahat; Jill A Helms
Journal:  Dent Mater       Date:  2020-07-07       Impact factor: 5.304

  5 in total

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