Literature DB >> 30175837

An anthraquinone-enzyme-peptide hybrid as a photo-switchable enzyme.

Shota Sotokawa1, Takashi Kitamura, Daisuke Takahashi, Kazunobu Toshima.   

Abstract

A purpose-designed anthraquinone-horseradish peroxidase (HRP)-cell penetrating peptide hybrid 1 showed high and effective cell permeability. Furthermore, 1 exhibited enzymatic activity without photo-irradiation, whereas significant self-degradation and loss of enzymatic activity occurred upon photo-irradiation in living cells.

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Year:  2018        PMID: 30175837     DOI: 10.1039/c8cc06130k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

Review 1.  Advances on Delivery of Cytotoxic Enzymes as Anticancer Agents.

Authors:  Akmal M Asrorov; Bahtiyor Muhitdinov; Bin Tu; Sharafitdin Mirzaakhmedov; Huiyuan Wang; Yongzhuo Huang
Journal:  Molecules       Date:  2022-06-14       Impact factor: 4.927

  1 in total

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