Literature DB >> 30175594

How Many Grays to Get to the Malfunction of Insulin Pumps? Determining the Effects of Radiation on Insulin Pump Function.

Angela L Magdaleno1, Gretchen A Perilli1, Marc A Vengrove1.   

Abstract

BACKGROUND: The primary objective was to determine if exposure to radiation has an effect on insulin pump function.
METHOD: Four donated insulin pumps were filled with saline and set to identical program modes. They were attached together with a dosimeter and exposed to repeat CT scans.
RESULTS: Insulin Pump 1 experienced a "Prime" alarm and a darkened screen during CT scan radiation exposure; this pump was removed from further radiation exposure after 6 CT scans. Insulin Pumps 2, 3, and 4 all continued to receive 34 more consecutive CT scan exposures with no significant alarms, failures, or malfunctions. Insulin Pump 4 experienced "Low Battery" and "Stuck Button" alarms, both of which were easily fixed. Insulin Pumps 2, 3, and 4 received a total of at least 8576 mrem from 34 CT scans worth of radiation without any significant alarms, malfunctions, or failures. Insulin Pump 1 was monitored after being removed from the study and continued to function normally with the darkened screen.
CONCLUSIONS: It cannot be determined whether Insulin Pump 1 had minor malfunctions due to repetitive use as a demonstration model or due to the radiation exposure. Insulin Pumps 2, 3, and 4 were monitored for 2 additional months following radiation exposure and continued to function normally. Further research studies with a larger number of insulin pumps are warranted to determine the true effect of radiation exposure on insulin pump function.

Entities:  

Keywords:  CT scan; diabetes mellitus; insulin pumps; radiation

Mesh:

Year:  2018        PMID: 30175594      PMCID: PMC6399791          DOI: 10.1177/1932296818796481

Source DB:  PubMed          Journal:  J Diabetes Sci Technol        ISSN: 1932-2968


  3 in total

1.  Implanted intrathecal drug delivery systems and radiation treatment.

Authors:  Rodolfo Gebhardt; Michelle Ludwig; Steve Kirsner; Kelly Kisling; Alyssa K Kosturakis
Journal:  Pain Med       Date:  2013-02-21       Impact factor: 3.750

Review 2.  Effect of radiation therapy on the latest generation of pacemakers and implantable cardioverter defibrillators: A systematic review.

Authors:  F Hudson; D Coulshed; E D'Souza; C Baker
Journal:  J Med Imaging Radiat Oncol       Date:  2010-02       Impact factor: 1.735

3.  Radiation-induced alarm and failure of an implanted programmable intrathecal pump.

Authors:  Hong Wu; Dian Wang
Journal:  Clin J Pain       Date:  2007 Nov-Dec       Impact factor: 3.442

  3 in total

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