Literature DB >> 3017370

Enhancement of gamma-aminobutyric acid receptor binding by protopine-type alkaloids.

J Kardos, G Blaskó, M Simonyi.   

Abstract

Protopine, cryptopine and allocryptopine were demonstrated to enhance 3H-gamma-aminobutyric acid (3H-GABA) binding to rat brain synaptic membrane receptors. The above finding might be indicative of benzodiazepine-like activity of these alkaloids.

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Year:  1986        PMID： 3017370

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN： 0004-4172


  3 in total

Review 1.  Identification and Quantification, Metabolism and Pharmacokinetics, Pharmacological Activities, and Botanical Preparations of Protopine: A Review.

Authors:  Wangli Huang; Lingbo Kong; Yang Cao; Liang Yan
Journal:  Molecules       Date:  2021-12-30       Impact factor: 4.411

2.  Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors.

Authors:  Milan Fedurco; Jana Gregorová; Kristýna Šebrlová; Jana Kantorová; Ondřej Peš; Roland Baur; Erwin Sigel; Eva Táborská
Journal:  Biochem Res Int       Date:  2015-10-05

3.  Anxiolytic-like effect of ethanolic extract of Argemone mexicana and its alkaloids in Wistar rats.

Authors:  Aideé Itzel Arcos-Martínez; Omar David Muñoz-Muñiz; Miguel Ángel Domínguez-Ortiz; Margarita Virginia Saavedra-Vélez; Maribel Vázquez-Hernández; María Gabriela Alcántara-López
Journal:  Avicenna J Phytomed       Date:  2016 Jul-Aug
  3 in total

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