Eric Toussirot1, Sébastien Aubry2, Michel Runge3. 1. Department of Rheumatology, University Hospital of Besançon, Clinical Investigation Center in Biotherapy, and University of Bourgogne Franche-Comté, Department of Therapeutics and EPILAB EA4266: Epigenetique des infections virales et des maladies inflammatoires; etoussirot@chu-besancon.fr. 2. Department of Radiology, and Nanomedicine Laboratory, INSERM EA4662, Université de Bourgogne Franche-Comté. 3. University Hospital of Besançon, Department of Radiology, Besançon, France.