Literature DB >> 30173127

Acute regrowth and dissemination of a mature spinal cord teratoma after partial resection.

Momotaro Kawai1, Narihito Nagoshi1, Akio Iwanami1,2, Shuji Mikami3, Osahiko Tsuji1, Nobuyuki Fujita1, Mitsuru Yagi1, Kota Watanabe1, Ken Ishii1,4,5, Masaya Nakamura1, Morio Matsumoto1.   

Abstract

A 23-year-old man presented with difficulty walking and leg pain and numbness. MRI revealed a cystic mass at Th11-12 and a pineal-region tumour. The patient underwent surgery to resect the thoracic-level mass. The tumour adhered strongly to the neural tissue and could only be partially resected. On pathological examination, the resected tumour was diagnosed as a mature teratoma. The tumour regrew and disseminated within 3 months after resection. Both the spinal cord tumour and the tumour in the pineal region shrank significantly after chemotherapy and radiotherapy. Although the tumour was pathologically diagnosed as a mature teratoma, we suspect that the residual tumour contained an immature or malignant component. Thus, careful follow-up observation is mandatory after partial resection of a mature teratoma. In addition, because teratomas can disseminate in the central nervous system, the presence of teratoma should prompt an examination of both the spinal cord and brain. © BMJ Publishing Group Limited 2018. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  CNS cancer; neurosurgery; orthopaedic and trauma surgery; orthopaedics; spinal cord

Mesh:

Year:  2018        PMID: 30173127     DOI: 10.1136/bcr-2017-223742

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  3 in total

1.  Pineal region teratoma with metastases in uncommon locations: a case report.

Authors:  Bayan AlRefaei; Taj Al Haj Husain; Ricarda Alwaw; Fatema Alzahraa Salama; Ghassan Hamzeh
Journal:  J Med Case Rep       Date:  2022-06-23

Review 2.  Rituximab therapy in pericarditis associated with rheumatoid arthritis.

Authors:  Ali Taylan
Journal:  Rheumatol Int       Date:  2022-01-05       Impact factor: 3.580

3.  Symptomatic mature teratoma of the lumbar spine: A case report.

Authors:  Coby Cunningham; Chiara Flores; Rocco Dabecco; Palgun Nisarga; Janice Ahn; Richard Williamson
Journal:  Surg Neurol Int       Date:  2022-01-12
  3 in total

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