Literature DB >> 30171885

Targeted management of influenza A/B outbreaks incorporating the cobas® Influenza A/B & RSV into the virology laboratory.

C F Lowe1, V Leung2, L Karakas3, L Merrick3, T Lawson3, M G Romney4, G Ritchie4, M Payne2.   

Abstract

During the 2017/18 influenza season, the authors' virology laboratory implemented the cobas® Influenza A/B & RSV (Roche Molecular Diagnostics, Pleasanton, CA, USA) for influenza outbreak management in two scenarios: initial outbreak investigation or at outbreak conclusion to avoid prolonged measures. Twenty-seven investigations were conducted, including declaration of 11 influenza A/B outbreaks. Thirty percent of investigations would have missed the standard batched daily laboratory-developed respiratory polymerase chain reaction (PCR), and delayed outbreak confirmation until the following day. The average reduction in turnaround time for influenza A/B testing was 10.2 h. A rapid molecular PCR in specific outbreak scenarios improved timely management of influenza outbreaks.
Copyright © 2018 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Influenza A/B; Outbreak; Rapid PCR; Virology

Mesh:

Year:  2018        PMID: 30171885     DOI: 10.1016/j.jhin.2018.08.014

Source DB:  PubMed          Journal:  J Hosp Infect        ISSN: 0195-6701            Impact factor:   3.926


  3 in total

1.  Impact of a PCR point of care test for influenza A/B on an acute medical unit in a large UK teaching hospital: results of an observational, pre and post intervention study.

Authors:  Mark I Garvey; Martyn A C Wilkinson; Craig W Bradley; Martin Biggs; Vinay Reddy-Kolanu; Husam Osman; Sarah Carmalt; Elisabeth Holden
Journal:  Antimicrob Resist Infect Control       Date:  2019-07-16       Impact factor: 4.887

2.  Performance evaluation of the Panther Fusion® respiratory tract panel.

Authors:  Jolanda J C Voermans; Daphne G J C Mulders; Suzan D Pas; Marion P G Koopmans; Annemiek A van der Eijk; Richard Molenkamp
Journal:  J Clin Virol       Date:  2019-12-10       Impact factor: 3.168

3.  Utility of Rapid Influenza Molecular Testing in an Outpatient Hemodialysis Unit: A Prospective Cohort Study.

Authors:  Matthew Kadatz; Michael Payne; Mercedeh Kiaii; Marc G Romney; Loretta Karakas; Tanya Lawson; Stan Marchuk; John Gill; Christopher F Lowe
Journal:  Can J Kidney Health Dis       Date:  2020-02-26
  3 in total

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