| Literature DB >> 30170941 |
Yoshiaki Kitamura1, Shuichi Moribe2, Yukio Kitade3.
Abstract
Glucosamino nucleic acids (GANAs) bearing a β-N-glycoside bond between carbon 1 of the glucosamine and the nucleobase nitrogen were synthesized and incorporated into oligonucleotides (4',6'-GANA and 3',6'-GANA). The thermal stability of oligonucleotide duplexes containing the GANA zwitterionic nucleotides was also investigated.Entities:
Keywords: Glucosamine; Nucleic acids; Oligonucleotides; Pyranosyl nucleosides; Zwitterionic nucleotides
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Year: 2018 PMID： 30170941 DOI： 10.1016/j.bmcl.2018.08.024
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823