| Literature DB >> 3016976 |
S Edwards, L Wood, C Hewitt-Taylor, T W Drew.
Abstract
Five calves were given live intranasal vaccine against bovid herpesvirus 1 (BHV1) two days after intranasal inoculation of bovine pestivirus (BVDV). Another 5 were vaccinated in the absence of BVDV. Control unvaccinated groups were also maintained. All calves were challenged with virulent BHV1. The unvaccinated calves developed signs of infectious bovine rhinotracheitis (IBR) and both vaccinated groups showed a similar degree of clinical protection from IBR. Those given BVDV before vaccination shed up to 140 times more BHV1 (P less than 0.01) in the nasal mucus following challenge than those which had received BHV1 vaccine alone. The epidemiological significance of this is discussed.Entities:
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Year: 1986 PMID： 3016976 DOI： 10.1007/bf02213992
Source DB: PubMed Journal: Vet Res Commun ISSN： 0165-7380 Impact factor: 2.459