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Literature DB >> 30166498

Infectious Mononucleosis and Lyme Disease as Confounding Diagnoses: A Report of 2 Cases.

Trever M Koester^1,2, Jennifer K Meece², Thomas R Fritsche^3,4, Holly M Frost^5,6,7.

Abstract

Lyme disease and infectious mononucleosis are common illnesses that share similar clinical presentations. Significant cross-reactivity is known to occur between Lyme and EBV serologic assays complicating the diagnosis. To date, no prior cases of concurrent acute Lyme and EBV infections have been reported. We describe the clinical presentation of two children with confirmed early Lyme disease and features suggestive of infectious mononucleosis, including one case of probable Lyme and EBV co-infection.

Entities: Disease Species

Keywords: Borrelia burgdorferi; Co-infection; Epstein-Barr virus; Infectious mononucleosis; Lyme disease

Mesh：

Year: 2018 PMID： 30166498 PMCID： PMC6306145 DOI： 10.3121/cmr.2018.1419

Source DB: PubMed Journal: Clin Med Res ISSN： 1539-4182

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References

8 in total

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Infectious Mononucleosis and Lyme Disease as Confounding Diagnoses: A Report of 2 Cases.

1. High frequency of false positive IgM immunoblots for Borrelia burgdorferi in clinical practice.

2. Lyme disease in Canada: Focus on children.

Review 3. Diagnosis of Lyme disease in the pediatric acute care setting.

4. How to use … the Monospot and other heterophile antibody tests.

5. Early Disseminated Lyme Disease Causing False-Positive Serology for Primary Epstein-Barr Virus Infection: Report of 2 Cases.

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8. Early Disseminated Lyme Disease Masquerading as Mononucleosis: A Case Report.