| Literature DB >> 3016334 |
T Clark, I Gresser, C Pfau, J Moss, D Woodrow.
Abstract
Infection of newborn C3HeB/FeJ mice with the arenavirus Pichinde resulted in stunted growth, severe liver cell degeneration, and death. Administration of sheep anti-mouse alpha/beta interferon globulin completely abrogated liver lesions in virus-infected mice, although it did not decrease the incidence of mortality. These results indicate that endogenous interferon may be responsible for some manifestations of viral disease.Entities:
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Year: 1986 PMID: 3016334 PMCID: PMC253249
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103