Literature DB >> 30160816

Analysis of Interactions between Telomeric i-Motif DNA and a Cyclic Tetraoxazole Compound.

Shadi Sedghi Masoud1, Yudai Yamaoki2, Yue Ma1, Adrien Marchand3, Fernaldo Richtia Winnerdy4, Valérie Gabelica3, Anh Tuân Phan4, Masato Katahira2, Kazuo Nagasawa1.   

Abstract

The interaction of a macrocyclic tetraoxazole compound, L2H2-4OTD (1), with two aminoalkyl side chains and telomeric i-motif, was investigated by means of electrophoretic mobility shift assay, circular dichroism spectroscopy, mass spectrometry and NMR spectroscopy analyses. The results indicate that 1 interacts with the i-motif structure at two preferred binding sites.
© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  DNA; G-quadruplexes; NMR spectroscopy; macrocycles; noncovalent interactions; tetraoxazole

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Year:  2018        PMID： 30160816     DOI： 10.1002/cbic.201800425

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


  1 in total

Review 1.  Recent progress of in-cell NMR of nucleic acids in living human cells.

Authors:  Yudai Yamaoki; Takashi Nagata; Tomoki Sakamoto; Masato Katahira
Journal:  Biophys Rev       Date:  2020-03-06
  1 in total

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