| Literature DB >> 30159807 |
Iqra Munir1, Ameer Fawad Zahoor2, Nasir Rasool1, Syed Ali Raza Naqvi1, Khalid Mahmood Zia3, Raheel Ahmad1.
Abstract
Chan-Lam coupling is one of the most popular and easy methods to perform arylation of amines (N-arylations). This cross-coupling is generally performed by reacting aryl boronate derivatives with a variety of substrates involving nitrogen containing functional groups such as amines, amides, ureas, hydrazine, carbamates. This article summarizes the synthetic applications of this reaction and the efforts of scientists to develop novel and efficient methodologies for this reaction.Entities:
Keywords: Boronic acids; Chan–Lam coupling; Cross-coupling reactions; N-Arylation; N-heterocycles
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Year: 2018 PMID: 30159807 DOI: 10.1007/s11030-018-9870-z
Source DB: PubMed Journal: Mol Divers ISSN: 1381-1991 Impact factor: 2.943