Literature DB >> 30158646

Quinohemanine, a quinoxalinone-bohemamine hybrid compound from Streptomyces sp. CPCC 200497.

Bingya Jiang1, Wei Zhao1, Shufen Li1, Hongyu Liu1, Liyan Yu1, Weixiao Niu1, Hongwei He1, Linzhuan Wu2.   

Abstract

A quinoxalinone-bohemamine hybrid compound quinohemanine (1), together with 1-methyl-2(H)-quinoxalin-2-one (2), was isolated from Streptomyces sp. CPCC 200497, a producer of quinomycins and bohemamines. Compounds 1 and 2 were purified using standard chromatographic methods, and their structures were defined through interpretation of HRMS, 1D, and 2D NMR data. Both 1 and 2 displayed moderate cytotoxicity against cancer cell line HepG2.

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Year:  2018        PMID: 30158646     DOI: 10.1038/s41429-018-0084-5

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  1 in total

1.  Synthesis of legonmycins A and B, C(7a)-hydroxylated bacterial pyrrolizidines.

Authors:  Wilfred J M Lewis; David M Shaw; Jeremy Robertson
Journal:  Beilstein J Org Chem       Date:  2021-02-02       Impact factor: 2.883

  1 in total

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