Literature DB >> 30157386

BETting on Novel Treatments for Asthma: Bromodomain 4 Inhibitors.

Yan Y Sanders1, Victor J Thannickal1.   

Abstract

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Year:  2019        PMID： 30157386      PMCID： PMC6835045          DOI： 10.1165/rcmb.2018-0271ED

Source DB:  PubMed          Journal:  Am J Respir Cell Mol Biol        ISSN： 1044-1549            Impact factor:   6.914


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  16 in total

Review 1.  Airway remodeling in asthma. Unanswered questions.

Authors:  J A Elias
Journal:  Am J Respir Crit Care Med       Date:  2000-03       Impact factor: 21.405

Review 2.  Epithelial-mesenchymal transitions in development and pathologies.

Authors:  Jean Paul Thiery
Journal:  Curr Opin Cell Biol       Date:  2003-12       Impact factor: 8.382

3.  Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA.

Authors:  Bo Huang; Xiao-Dong Yang; Ming-Ming Zhou; Keiko Ozato; Lin-Feng Chen
Journal:  Mol Cell Biol       Date:  2008-12-22       Impact factor: 4.272

Review 4.  Histone acetylation and deacetylation: importance in inflammatory lung diseases.

Authors:  P J Barnes; I M Adcock; K Ito
Journal:  Eur Respir J       Date:  2005-03       Impact factor: 16.671

5.  BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses.

Authors:  Anna C Belkina; Barbara S Nikolajczyk; Gerald V Denis
Journal:  J Immunol       Date:  2013-02-18       Impact factor: 5.422

Review 6.  The role of human bromodomains in chromatin biology and gene transcription.

Authors:  Roberto Sanchez; Ming-Ming Zhou
Journal:  Curr Opin Drug Discov Devel       Date:  2009-09

Review 7.  Novel concepts in airway inflammation and remodelling in asthma.

Authors:  Sejal Saglani; Clare M Lloyd
Journal:  Eur Respir J       Date:  2015-11-05       Impact factor: 16.671

8.  CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET.

Authors:  Rachel L Clifford; Jamie K Patel; Alison E John; Amanda L Tatler; Lisa Mazengarb; Christopher E Brightling; Alan J Knox
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2015-02-20       Impact factor: 5.464

9.  Bromodomain and Extra-Terminal Protein Inhibition Attenuates Neutrophil-dominant Allergic Airway Disease.

Authors:  Michelle L Manni; Sivanarayana Mandalapu; Andres Salmeron; Jose M Lora; Jay K Kolls; John F Alcorn
Journal:  Sci Rep       Date:  2017-02-24       Impact factor: 4.379

Review 10.  Selectivity on-target of bromodomain chemical probes by structure-guided medicinal chemistry and chemical biology.

Authors:  Carles Galdeano; Alessio Ciulli
Journal:  Future Med Chem       Date:  2016-05-19       Impact factor: 3.808
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  1 in total

Review 1.  The Role of CD4+ T Cells and Microbiota in the Pathogenesis of Asthma.

Authors:  Jiung Jeong; Heung Kyu Lee
Journal:  Int J Mol Sci       Date:  2021-10-31       Impact factor: 5.923
  1 in total

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