Literature DB >> 30156856

N, N'-Di(acylamino)-2,5-diketopiperazines: Strategic Incorporation of Reciprocal n → π* Interactions in a Druglike Scaffold.

Abdur Rahim1, Biswajit Sahariah1, Bani Kanta Sarma1.   

Abstract

The incorporation of the recently discovered reciprocal n → π* interactions in 2,5-diketopiperazines (DKPs) is reported to design a novel N, N'-di(acylamino)-2,5-diketopiperazine (daa-DKP) scaffold. The design, synthesis, and structural features of daa-DKPs and the effect of reciprocal n → π* interactions in their structural rigidity is discussed.

Entities:  

Year:  2018        PMID： 30156856     DOI： 10.1021/acs.orglett.8b02449

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  n→π* Interactions Modulate the Disulfide Reduction Potential of Epidithiodiketopiperazines.

Authors:  Henry R Kilgore; Chase R Olsson; Kyan A D'Angelo; Mohammad Movassaghi; Ronald T Raines
Journal:  J Am Chem Soc       Date:  2020-08-21       Impact factor: 15.419

2.  Relative orientation of the carbonyl groups determines the nature of orbital interactions in carbonyl-carbonyl short contacts.

Authors:  Biswajit Sahariah; Bani Kanta Sarma
Journal:  Chem Sci       Date:  2018-10-29       Impact factor: 9.825

3.  Phenoxy pendant isatins as potent α-glucosidase inhibitors: reciprocal carbonyl⋯carbonyl interactions, antiparallel π⋯π stacking driven solid state self-assembly and biological evaluation.

Authors:  Saba Mehreen; Mehwash Zia; Ajmal Khan; Javid Hussain; Saeed Ullah; Muhammad U Anwar; Ahmed Al-Harrasi; Muhammad Moazzam Naseer
Journal:  RSC Adv       Date:  2022-07-21       Impact factor: 4.036

Review 4.  Diketopiperazine Gels: New Horizons from the Self-Assembly of Cyclic Dipeptides.

Authors:  Marco Scarel; Silvia Marchesan
Journal:  Molecules       Date:  2021-06-03       Impact factor: 4.411
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.