| Literature DB >> 3015669 |
G M Andrei, J S Lampuri, C E Coto, R A de Torres.
Abstract
Treatment of neonatal mice with an antiviral factor, (AVF), obtained from the leaves of Melia azedarach L. protected them against lethal encephalitis caused by Tacaribe virus inoculation. The degree of protection obtained varied from 66% to 100% depending on the virus dose. Similarly, administration of AVF to nursing mothers protected their offspring from developing virus encephalitis. AVF does not directly inactivate Tacaribe virus; it inhibits an early step (s) in the replication process in cell cultures.Entities:
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Year: 1986 PMID： 3015669 DOI： 10.1007/bf01941548
Source DB: PubMed Journal: Experientia ISSN： 0014-4754