Literature DB >> 30155777

A simple influenza model with complicated dynamics.

M G Roberts1, R I Hickson2,3, J M McCaw3,4, L Talarmain5,6.   

Abstract

We propose and analyse a model for the dynamics of a single strain of an influenza-like infection. The model incorporates waning acquired immunity to infection and punctuated antigenic drift of the virus, employing a set of differential equations within a season and a discrete map between seasons. We show that the between-season map displays a variety of qualitatively different dynamics: fixed points, periodic solutions, or more complicated behaviour suggestive of chaos. For some example parameters we demonstrate the existence of two distinct basins of attraction, that is the initial conditions determine the long term dynamics. Our results suggest that there is no reason to expect influenza dynamics to be regular, or to expect past epidemics to give a clear indication of future seasons' behaviour.

Entities:  

Keywords:  Discrete dynamics; Dynamical systems; Seasonal influenza; Transmission model

Year:  2018        PMID: 30155777     DOI: 10.1007/s00285-018-1285-z

Source DB:  PubMed          Journal:  J Math Biol        ISSN: 0303-6812            Impact factor:   2.259


  14 in total

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5.  The impact of seasonal and year-round transmission regimes on the evolution of influenza A virus.

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Review 6.  Capturing the dynamics of pathogens with many strains.

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Journal:  J Math Biol       Date:  2015-03-24       Impact factor: 2.259

7.  A simple parasite model with complicated dynamics.

Authors:  M G Roberts; J A Heesterbeek
Journal:  J Math Biol       Date:  1998-09       Impact factor: 2.259

8.  Epidemiological effects of seasonal oscillations in birth rates.

Authors:  Daihai He; David J D Earn
Journal:  Theor Popul Biol       Date:  2007-05-07       Impact factor: 1.570

9.  Nextstrain: real-time tracking of pathogen evolution.

Authors:  James Hadfield; Colin Megill; Sidney M Bell; John Huddleston; Barney Potter; Charlton Callender; Pavel Sagulenko; Trevor Bedford; Richard A Neher
Journal:  Bioinformatics       Date:  2018-12-01       Impact factor: 6.931

10.  Generality of the final size formula for an epidemic of a newly invading infectious disease.

Authors:  Junling Ma; David J D Earn
Journal:  Bull Math Biol       Date:  2006-04-08       Impact factor: 1.758

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  1 in total

1.  Multistability of a Two-Dimensional Map Arising in an Influenza Model.

Authors:  Yu-Jhe Huang; Hsuan Te Huang; Jonq Juang; Cheng-Han Wu
Journal:  J Nonlinear Sci       Date:  2021-12-28       Impact factor: 3.621

  1 in total

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