| Literature DB >> 301557 |
E Thorsby, A Helgesen, B G Solheim, B Vandvik.
Abstract
The frequency of the MLC activating HLA-Dw2 determinant was found significantly increased to 68% among 37 patients with long-standing multiple sclerosis, compared to 30.2% among healthy controls. A similar (or stronger) degree of association was found with an "Ia-like" B cell specificity, SOW, while the association with HLA-B7 was less apparent. No correlation between HLA-Dw2 and signs of local synthesis of oligoclonal IgG or measles or rubella virus antibodies in the CNS was observed.Entities:
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Year: 1977 PMID： 301557 DOI： 10.1016/0022-510x(77)90233-7
Source DB: PubMed Journal: J Neurol Sci ISSN： 0022-510X Impact factor: 3.181