Duygu Erdem1, Yavuz Fuat Yılmaz2, Müge Özcan3, Ali Titiz4, Samet Özlügedik5, Adnan Ünal6. 1. Department of Otorhinolaryngology, Faculty of Medicine, Bülent Ecevit University, Zonguldak, Turkey. duygualtuntas@gmail.com. 2. Department of Otorhinolaryngology, Health Sciences University, Gülhane Faculty of Medicine, Ankara, Turkey. 3. Department of Otorhinolaryngology, Numune Training and Research Hospital, Health Sciences University, Ankara, Turkey. 4. Department of Otorhinolaryngology, Acibadem Ankara Hospital, Ankara, Turkey. 5. Department of Otorhinolaryngology, Health Sciences University, Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Turkey. 6. Department of Otorhinolaryngology, Ekol Hospitals, İzmir, Turkey.
Abstract
PURPOSE: To investigate the relationship between sleep-disordered breathing with gastroesophageal reflux (GER) and laryngopharyngeal reflux (LPR) using a two-channel triple-sensor pHmetry catheter. METHODS: The study was carried out on a total of 34 people with complaints of snoring, witnessed apnea and daytime sleepiness. 24-h pH monitoring with a two-channel, triple-sensor antimony pH catheter was applied to individuals simultaneously with polysomnography (PSG) on the day they would sleep in the sleep laboratory. Obstructive sleep apnea syndrome (OSAS) severity and reflux grade were compared with each other. Data obtained from PSG and pHmetry results were numerically compared with each other. The relationship between apnea, hypopnea, and arousal periods and reflux episodes was then examined by overlaying pHmetry graphics for each patient. RESULTS: A total of 34 individuals (18 males-52.9% and 16 females-47.1%), age ranging from 27 to 71 years (mean 50.5 ± 11.0) participated in the study. GER was detected in 52.9% and LPR in 85.3% of the patients. In 35.3% of cases, pathologic GER was not observed despite LPR detection. No statistically significant relationship was found between the numerical values of apnea-hypopnea index (AHI) and arousal numbers and reflux parameters of individuals and between OSAS severity and LPR and GER (p > 0.05). There was no statistically significant correlation between respiratory events and reflux episodes with regard to timing (p > 0.05). CONCLUSION: The prevalence of GER and LPR is found to be high in patients with sleep-disordered breathing. There is no significant relationship between OSAS severity and GER and LPR grade or respiratory events and reflux episodes with regard to timing.
PURPOSE: To investigate the relationship between sleep-disordered breathing with gastroesophageal reflux (GER) and laryngopharyngeal reflux (LPR) using a two-channel triple-sensor pHmetry catheter. METHODS: The study was carried out on a total of 34 people with complaints of snoring, witnessed apnea and daytime sleepiness. 24-h pH monitoring with a two-channel, triple-sensor antimony pH catheter was applied to individuals simultaneously with polysomnography (PSG) on the day they would sleep in the sleep laboratory. Obstructive sleep apnea syndrome (OSAS) severity and reflux grade were compared with each other. Data obtained from PSG and pHmetry results were numerically compared with each other. The relationship between apnea, hypopnea, and arousal periods and reflux episodes was then examined by overlaying pHmetry graphics for each patient. RESULTS: A total of 34 individuals (18 males-52.9% and 16 females-47.1%), age ranging from 27 to 71 years (mean 50.5 ± 11.0) participated in the study. GER was detected in 52.9% and LPR in 85.3% of the patients. In 35.3% of cases, pathologic GER was not observed despite LPR detection. No statistically significant relationship was found between the numerical values of apnea-hypopnea index (AHI) and arousal numbers and reflux parameters of individuals and between OSAS severity and LPR and GER (p > 0.05). There was no statistically significant correlation between respiratory events and reflux episodes with regard to timing (p > 0.05). CONCLUSION: The prevalence of GER and LPR is found to be high in patients with sleep-disordered breathing. There is no significant relationship between OSAS severity and GER and LPR grade or respiratory events and reflux episodes with regard to timing.
Authors: Chad A Morse; Stuart F Quan; Mary Z Mays; Colleen Green; George Stephen; Ronnie Fass Journal: Clin Gastroenterol Hepatol Date: 2004-09 Impact factor: 11.382