Literature DB >> 30155623

Mesenchymal Stem Cells as Endogenous Regulators of Inflammation.

Hafsa Munir1, Lewis S C Ward2, Helen M McGettrick3.   

Abstract

This chapter discusses the regulatory role of endogenous mesenchymal stem cells (MSC) during an inflammatory response. MSC are a heterogeneous population of multipotent cells that normally contribute towards tissue maintenance and repair but have garnered significant scientific interest for their potent immunomodulatory potential. It is through these physicochemical interactions that MSC are able to exert an anti-inflammatory response on neighbouring stromal and haematopoietic cells. However, the impact of the chronic inflammatory environment on MSC function remains to be determined. Understanding the relationship of MSC between resolution of inflammation and autoimmunity will both offer new insights in the use of MSC as a therapeutic, and also their involvement in the pathogenesis of inflammatory disorders.

Entities:  

Keywords:  Endothelial cells; Lymphocytes; Mesenchymal stem cells; Neutrophils

Mesh：

Year:  2018        PMID： 30155623     DOI： 10.1007/978-3-319-78127-3_5

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  10 in total

1.  The Therapeutic Effect of iMSC-Derived Small Extracellular Vesicles on Tendinopathy Related Pain Through Alleviating Inflammation: An in vivo and in vitro Study.

Authors:  Zhaochen Zhu; Renzhi Gao; Teng Ye; Kai Feng; Juntao Zhang; Yu Chen; Zongping Xie; Yang Wang
Journal:  J Inflamm Res       Date:  2022-03-01

2.  Treatment with Mesenchymal-Derived Extracellular Vesicles Reduces Injury-Related Pathology in Pyramidal Neurons of Monkey Perilesional Ventral Premotor Cortex.

Authors:  Maria Medalla; Wayne Chang; Samantha M Calderazzo; Veronica Go; Alexandra Tsolias; Joseph W Goodliffe; Dhruba Pathak; Diego De Alba; Monica Pessina; Douglas L Rosene; Benjamin Buller; Tara L Moore
Journal:  J Neurosci       Date:  2020-04-02       Impact factor: 6.167

3.  Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model.

Authors:  Zhengzhou Shi; Qi Wang; Youbo Zhang; Dapeng Jiang
Journal:  Stem Cell Res Ther       Date:  2020-06-26       Impact factor: 6.832

Review 4.  Proresolving Lipid Mediators and Receptors in Stem Cell Biology: Concise Review.

Authors:  Mario Romano; Sara Patruno; Antonella Pomilio; Antonio Recchiuti
Journal:  Stem Cells Transl Med       Date:  2019-06-12       Impact factor: 6.940

5.  Extracellular vesicles released from hiPSC-derived MSCs attenuate chronic prostatitis/chronic pelvic pain syndrome in rats by immunoregulation.

Authors:  Xufeng Peng; Hailin Guo; Ji Yuan; Yu Chen; Yuguo Xia; Lin Wang; Ying Wang; Yichen Huang; Hua Xie; Yang Wang; Fang Chen
Journal:  Stem Cell Res Ther       Date:  2021-03-20       Impact factor: 6.832

Review 6.  Fibronectin in Fracture Healing: Biological Mechanisms and Regenerative Avenues.

Authors:  Jonathan Klavert; Bram C J van der Eerden
Journal:  Front Bioeng Biotechnol       Date:  2021-04-16

7.  Bridging Insights From Lymph Node and Synovium Studies in Early Rheumatoid Arthritis.

Authors:  Aoife M O'Byrne; Tineke A de Jong; Lisa G M van Baarsen
Journal:  Front Med (Lausanne)       Date:  2022-01-14

Review 8.  Regulation of the mesenchymal stem cell fate by interleukin-17: Implications in osteogenic differentiation.

Authors:  Jelena Krstić; Slavko Mojsilović; Sonja S Mojsilović; Juan F Santibanez
Journal:  World J Stem Cells       Date:  2021-11-26       Impact factor: 5.326

9.  The Intrapericardial Delivery of Extracellular Vesicles from Cardiosphere-Derived Cells Stimulates M2 Polarization during the Acute Phase of Porcine Myocardial Infarction.

Authors:  Esther López; Rebeca Blázquez; Federica Marinaro; Verónica Álvarez; Virginia Blanco; Claudia Báez; Irene González; Ana Abad; Beatriz Moreno; Francisco Miguel Sánchez-Margallo; Verónica Crisóstomo; Javier García Casado
Journal:  Stem Cell Rev Rep       Date:  2020-06       Impact factor: 5.739

Review 10.  Age-related cerebral small vessel disease and inflammaging.

Authors:  Tiemei Li; Yinong Huang; Wei Cai; Xiaodong Chen; Xuejiao Men; Tingting Lu; Aiming Wu; Zhengqi Lu
Journal:  Cell Death Dis       Date:  2020-10-30       Impact factor: 8.469
  10 in total

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