Literature DB >> 30154567

Mechanisms of mitophagy in cellular homeostasis, physiology and pathology.

Konstantinos Palikaras1,2, Eirini Lionaki1, Nektarios Tavernarakis3,4.   

Abstract

Mitophagy is an evolutionarily conserved cellular process to remove dysfunctional or superfluous mitochondria, thus fine-tuning mitochondrial number and preserving energy metabolism. In this Review, we survey recent advances towards elucidating the molecular mechanisms that mediate mitochondrial elimination and the signalling pathways that govern mitophagy. We consider the contributions of mitophagy in physiological and pathological contexts and discuss emerging findings, highlighting the potential value of mitophagy modulation in therapeutic intervention.

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Year:  2018        PMID： 30154567     DOI： 10.1038/s41556-018-0176-2

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  280 in total

1.  Drosophila MICOS knockdown impairs mitochondrial structure and function and promotes mitophagy in muscle tissue.

Authors:  Li-Jie Wang; Tian Hsu; Hsiang-Ling Lin; Chi-Yu Fu
Journal:  Biol Open       Date:  2020-12-02       Impact factor: 2.422

Review 2.  Role of autophagy in alcohol and drug-induced liver injury.

Authors:  Jessica A Williams; Wen-Xing Ding
Journal:  Food Chem Toxicol       Date:  2019-12-23       Impact factor: 6.023

Review 3.  Mitochondria in the maintenance of hematopoietic stem cells: new perspectives and opportunities.

Authors:  Marie-Dominique Filippi; Saghi Ghaffari
Journal:  Blood       Date:  2019-02-26       Impact factor: 22.113

4.  Autophagy, apoptosis, and mitochondria: molecular integration and physiological relevance in skeletal muscle.

Authors:  Darin Bloemberg; Joe Quadrilatero
Journal:  Am J Physiol Cell Physiol       Date:  2019-04-24       Impact factor: 4.249

Review 5.  Mitophagy in tumorigenesis and metastasis.

Authors:  Logan P Poole; Kay F Macleod
Journal:  Cell Mol Life Sci       Date:  2021-02-13       Impact factor: 9.261

6.  LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10.

Authors:  Fieke Wauters; Tom Cornelissen; Dorien Imberechts; Shaun Martin; Brianada Koentjoro; Carolyn Sue; Peter Vangheluwe; Wim Vandenberghe
Journal:  Autophagy       Date:  2019-04-19       Impact factor: 16.016

Review 7.  Aging-Dependent Mitophagy Dysfunction in Alzheimer's Disease.

Authors:  Mingxue Song; Xiulan Zhao; Fuyong Song
Journal:  Mol Neurobiol       Date:  2021-01-08       Impact factor: 5.590

Review 8.  Mitochondrial pathways in human health and aging.

Authors:  Rebecca Bornstein; Brenda Gonzalez; Simon C Johnson
Journal:  Mitochondrion       Date:  2020-07-30       Impact factor: 4.160

Review 9.  Mitochondrial damage & lipid signaling in traumatic brain injury.

Authors:  Andrew M Lamade; Tamil S Anthonymuthu; Zachary E Hier; Yuan Gao; Valerian E Kagan; Hülya Bayır
Journal:  Exp Neurol       Date:  2020-04-11       Impact factor: 5.330

Review 10.  Mitophagy in cardiovascular homeostasis.

Authors:  Ruohan Zhang; Judith Krigman; Hongke Luo; Serra Ozgen; Mingchong Yang; Nuo Sun
Journal:  Mech Ageing Dev       Date:  2020-04-11       Impact factor: 5.432
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