Marek Krzystanek1, Mariusz Borkowski2, Katarzyna Skałacka3, Krzysztof Krysta2. 1. Department of Psychiatric Rehabilitation, Department of Psychiatry and Psychotherapy, Medical School of Silesia, Ziolowa 45/47 Street, 40-635 Katowice, Poland.. Electronic address: m.krzystanek@sum.edu.pl. 2. Department of Psychiatric Rehabilitation, Department of Psychiatry and Psychotherapy, Medical School of Silesia, Ziolowa 45/47 Street, 40-635 Katowice, Poland. 3. Institute of Psychology, University of Opole, Kopernika 11A Street, 45-040 Opole, Poland.
Abstract
OBJECTIVE: The study objective was to test a smartphone-based MONEO platform designed to improve the clinical condition of paranoid schizophrenia patients. Telemedicine treatment is considered to be as effective as traditional treatment in outpatient clinics. METHOD: A total of 290 patients with paranoid schizophrenia in the symptomatic remission state were recruited to this 12-month multicenter, open-label randomized trial. A study group (n = 191) received a smartphone with the MONEO platform installed. Patients conducted cognitive training twice a week. Patients' mental state was assessed every month via teleconference. A placebo group (n = 99) received a platform with functionality limited to monthly teleconsultation and performing cognitive training every 6 months. The clinical status was measured using the Positive and Negative Syndrome Scale (PANSS), Calgary, and Clinical Global Impression-Severity (CGI-S) clinical scales. RESULTS: After 12 months, a significant reduction of symptoms was observed in the study group, as assessed using the Calgary (36%, P < 0.01) and PANSS (8.6%, P < 0.05) scales. Symptom reduction of 23.6% was also observed in the placebo group (P < 0.05, Calgary scale). In the study group, depression, positive symptoms, excitement, general psychopathology and disorganization subscales decreased significantly, while in the placebo group, only the depression subscale decreased. The greatest improvement of 11.2% (study group, P < 0.05), vs 16.2% (placebo group, P < 0.05), was observed for the depression subscale. CONCLUSION: The MONEO platform was demonstrated to positively influence the clinical condition of individuals with paranoid schizophrenia. A lack of negative consequences associated with usage of the device was also reported.
RCT Entities:
OBJECTIVE: The study objective was to test a smartphone-based MONEO platform designed to improve the clinical condition of paranoid schizophreniapatients. Telemedicine treatment is considered to be as effective as traditional treatment in outpatient clinics. METHOD: A total of 290 patients with paranoid schizophrenia in the symptomatic remission state were recruited to this 12-month multicenter, open-label randomized trial. A study group (n = 191) received a smartphone with the MONEO platform installed. Patients conducted cognitive training twice a week. Patients' mental state was assessed every month via teleconference. A placebo group (n = 99) received a platform with functionality limited to monthly teleconsultation and performing cognitive training every 6 months. The clinical status was measured using the Positive and Negative Syndrome Scale (PANSS), Calgary, and Clinical Global Impression-Severity (CGI-S) clinical scales. RESULTS: After 12 months, a significant reduction of symptoms was observed in the study group, as assessed using the Calgary (36%, P < 0.01) and PANSS (8.6%, P < 0.05) scales. Symptom reduction of 23.6% was also observed in the placebo group (P < 0.05, Calgary scale). In the study group, depression, positive symptoms, excitement, general psychopathology and disorganization subscales decreased significantly, while in the placebo group, only the depression subscale decreased. The greatest improvement of 11.2% (study group, P < 0.05), vs 16.2% (placebo group, P < 0.05), was observed for the depression subscale. CONCLUSION: The MONEO platform was demonstrated to positively influence the clinical condition of individuals with paranoid schizophrenia. A lack of negative consequences associated with usage of the device was also reported.
Authors: Christina Gallinat; Markus Moessner; Sandra Apondo; Philipp A Thomann; Sabine C Herpertz; Stephanie Bauer Journal: Int J Environ Res Public Health Date: 2021-11-25 Impact factor: 3.390
Authors: Morten Lindbjerg Tønning; Lars Vedel Kessing; Jakob Eivind Bardram; Maria Faurholt-Jepsen Journal: J Med Internet Res Date: 2019-10-27 Impact factor: 5.428