Literature DB >> 3015345

Intrastriatal N-methyl-D-aspartate prevents amygdala kindled seizures in rats.

E A Cavalheiro, L Turski.   

Abstract

Microinfusion of an excitatory amino acid, N-methyl-D-aspartate, into the ventral mid-striatum in the rat protects from amygdala kindled seizures. This result demonstrates that excitatory activity in the striatum modulates the threshold for seizures in the limbic forebrain.

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Year:  1986        PMID： 3015345     DOI： 10.1016/0006-8993(86)91204-7

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  5 in total

1.  Effect of septal kindling on glutamate binding and calcium/calmodulin-dependent phosphorylation in a postsynaptic density fraction isolated from rat cerebral cortex.

Authors:  K Wu; C Wasterlain; L Sachs; P Siekevitz
Journal:  Proc Natl Acad Sci U S A       Date:  1990-07       Impact factor: 11.205

2.  The basal ganglia, the deep prepyriform cortex, and seizure spread: bicuculline is anticonvulsant in the rat striatum.

Authors:  L Turski; E A Cavalheiro; L S Calderazzo-Filho; Z A Bortolotto; T Klockgether; C Ikonomidou; W A Turski
Journal:  Proc Natl Acad Sci U S A       Date:  1989-03       Impact factor: 11.205

3.  It's a Storm, It's a Gale: Epilepsy Initiation From the Corticostriatal Circuit.

Authors:  Libor Velíšek
Journal:  Epilepsy Curr       Date:  2019-08-27       Impact factor: 7.500

Review 4.  Bypassing the Blood-Brain Barrier: Direct Intracranial Drug Delivery in Epilepsies.

Authors:  Manuela Gernert; Malte Feja
Journal:  Pharmaceutics       Date:  2020-11-24       Impact factor: 6.321

5.  Differential patterns of synaptotagmin7 mRNA expression in rats with kainate- and pilocarpine-induced seizures.

Authors:  Gordana Glavan; Ronald Eugene See; Marko Živin
Journal:  PLoS One       Date:  2012-05-02       Impact factor: 3.240
  5 in total

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