Literature DB >> 30153136

Emerging therapeutic potential of glycine in cardiometabolic diseases: dual benefits in lipid and glucose metabolism.

Oren Rom1, Luis Villacorta1, Jifeng Zhang1, Y Eugene Chen1, Michael Aviram2.   

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Year:  2018        PMID： 30153136      PMCID： PMC6198663          DOI： 10.1097/MOL.0000000000000543

Source DB:  PubMed          Journal:  Curr Opin Lipidol        ISSN： 0957-9672            Impact factor:   4.776


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  27 in total

1.  Contribution of dietary amino acids composition to incidence of cardiovascular outcomes: A prospective population-based study.

Authors:  P Mirmiran; Z Bahadoran; A Ghasemi; F Azizi
Journal:  Nutr Metab Cardiovasc Dis       Date:  2017-05-15       Impact factor: 4.222

Review 2.  Metabolomics and Metabolic Diseases: Where Do We Stand?

Authors:  Christopher B Newgard
Journal:  Cell Metab       Date:  2016-10-27       Impact factor: 27.287

3.  Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance.

Authors:  Melania Gaggini; Fabrizia Carli; Chiara Rosso; Emma Buzzigoli; Milena Marietti; Veronica Della Latta; Demetrio Ciociaro; Maria Lorena Abate; Roberto Gambino; Maurizio Cassader; Elisabetta Bugianesi; Amalia Gastaldelli
Journal:  Hepatology       Date:  2017-11-17       Impact factor: 17.425

Review 4.  Serum and plasma amino acids as markers of prediabetes, insulin resistance, and incident diabetes.

Authors:  C Gar; M Rottenkolber; C Prehn; J Adamski; J Seissler; A Lechner
Journal:  Crit Rev Clin Lab Sci       Date:  2017-12-14       Impact factor: 6.250

5.  Improved Cardiovascular Function in Old Mice After N-Acetyl Cysteine and Glycine Supplemented Diet: Inflammation and Mitochondrial Factors.

Authors:  Katarzyna A Cieslik; Rajagopal V Sekhar; Alejandro Granillo; Anilkumar Reddy; Guillermo Medrano; Celia Pena Heredia; Mark L Entman; Dale J Hamilton; Shumin Li; Erin Reineke; Anisha A Gupte; Aijun Zhang; George E Taffet
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2018-08-10       Impact factor: 6.053

6.  Cardiovascular safety and efficacy of the PCSK9 inhibitor evolocumab in patients with and without diabetes and the effect of evolocumab on glycaemia and risk of new-onset diabetes: a prespecified analysis of the FOURIER randomised controlled trial.

Authors:  Marc S Sabatine; Lawrence A Leiter; Stephen D Wiviott; Robert P Giugliano; Prakash Deedwania; Gaetano M De Ferrari; Sabina A Murphy; Julia F Kuder; Ioanna Gouni-Berthold; Basil S Lewis; Yehuda Handelsman; Armando Lira Pineda; Narimon Honarpour; Anthony C Keech; Peter S Sever; Terje R Pedersen
Journal:  Lancet Diabetes Endocrinol       Date:  2017-09-15       Impact factor: 32.069

7.  Glycine restores glutathione and protects against oxidative stress in vascular tissue from sucrose-fed rats.

Authors:  Angélica Ruiz-Ramírez; Ely Ortiz-Balderas; Guillermo Cardozo-Saldaña; Eulises Diaz-Diaz; Mohammed El-Hafidi
Journal:  Clin Sci (Lond)       Date:  2014-01-01       Impact factor: 6.124

Review 8.  Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention.

Authors:  Zobair Younossi; Quentin M Anstee; Milena Marietti; Timothy Hardy; Linda Henry; Mohammed Eslam; Jacob George; Elisabetta Bugianesi
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2017-09-20       Impact factor: 46.802

9.  Atherogenicity of amino acids in the lipid-laden macrophage model system in vitro and in atherosclerotic mice: a key role for triglyceride metabolism.

Authors:  Oren Rom; Claudia Grajeda-Iglesias; Mahmoud Najjar; Niroz Abu-Saleh; Nina Volkova; Dalit Esther Dar; Tony Hayek; Michael Aviram
Journal:  J Nutr Biochem       Date:  2017-04-06       Impact factor: 6.048

10.  A Glycine-Insulin Autocrine Feedback Loop Enhances Insulin Secretion From Human β-Cells and Is Impaired in Type 2 Diabetes.

Authors:  Richard Yan-Do; Eric Duong; Jocelyn E Manning Fox; Xiaoqing Dai; Kunimasa Suzuki; Shara Khan; Austin Bautista; Mourad Ferdaoussi; James Lyon; Xichen Wu; Stephen Cheley; Patrick E MacDonald; Matthias Braun
Journal:  Diabetes       Date:  2016-05-03       Impact factor: 9.461
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  6 in total

1.  Glycine regulates mucosal immunity and the intestinal microbial composition in weaned piglets.

Authors:  Yun Ji; Xiaoxiao Fan; Yunchang Zhang; Ju Li; Zhaolai Dai; Zhenlong Wu
Journal:  Amino Acids       Date:  2021-04-11       Impact factor: 3.520

2.  Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome.

Authors:  Oren Rom; Yuhao Liu; Zhipeng Liu; Ying Zhao; Jianfeng Wu; Alia Ghrayeb; Luis Villacorta; Yanbo Fan; Lin Chang; Lu Wang; Cai Liu; Dongshan Yang; Jun Song; Jason C Rech; Yanhong Guo; Huilun Wang; Guizhen Zhao; Wenying Liang; Yui Koike; Haocheng Lu; Tomonari Koike; Tony Hayek; Subramaniam Pennathur; Chuanwu Xi; Bo Wen; Duxin Sun; Minerva T Garcia-Barrio; Michael Aviram; Eyal Gottlieb; Inbal Mor; Wanqing Liu; Jifeng Zhang; Y Eugene Chen
Journal:  Sci Transl Med       Date:  2020-12-02       Impact factor: 17.956

3.  Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis.

Authors:  Oren Rom; Yuhao Liu; Alexandra C Finney; Alia Ghrayeb; Ying Zhao; Yousef Shukha; Lu Wang; Krishani K Rajanayake; Sandeep Das; Nabil A Rashdan; Natan Weissman; Luisa Delgadillo; Bo Wen; Minerva T Garcia-Barrio; Michael Aviram; Christopher G Kevil; Arif Yurdagul; Christopher B Pattillo; Jifeng Zhang; Duxin Sun; Tony Hayek; Eyal Gottlieb; Inbal Mor; Y Eugene Chen
Journal:  Redox Biol       Date:  2022-04-13       Impact factor: 10.787

4.  Dysregulated oxalate metabolism is a driver and therapeutic target in atherosclerosis.

Authors:  Yuhao Liu; Ying Zhao; Yousef Shukha; Haocheng Lu; Lu Wang; Zhipeng Liu; Cai Liu; Yang Zhao; Huilun Wang; Guizhen Zhao; Wenying Liang; Yanbo Fan; Lin Chang; Arif Yurdagul; Christopher B Pattillo; A Wayne Orr; Michael Aviram; Bo Wen; Minerva T Garcia-Barrio; Jifeng Zhang; Wanqing Liu; Duxin Sun; Tony Hayek; Y Eugene Chen; Oren Rom
Journal:  Cell Rep       Date:  2021-07-27       Impact factor: 9.423

5.  Soybean Oil Modulates the Gut Microbiota Associated with Atherogenic Biomarkers.

Authors:  Hila Korach-Rechtman; Oren Rom; Lirane Mazouz; Shay Freilich; Helana Jeries; Tony Hayek; Michael Aviram; Yechezkel Kashi
Journal:  Microorganisms       Date:  2020-03-30

Review 6.  Atherosclerosis Linked to Aberrant Amino Acid Metabolism and Immunosuppressive Amino Acid Catabolizing Enzymes.

Authors:  Bozidarka L Zaric; Jelena N Radovanovic; Zoran Gluvic; Alan J Stewart; Magbubah Essack; Olaa Motwalli; Takashi Gojobori; Esma R Isenovic
Journal:  Front Immunol       Date:  2020-09-28       Impact factor: 7.561
  6 in total

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