Non-Directed Cross-Dehydrogenative (Hetero)arylation of Allylic C(sp3 )-H bonds enabled by C-H Activation.

Herein, we report the selective, non-directed and cross-dehydrogenative coupling of allylic C(sp3 )-H bonds with C(sp2 )-H bonds of (hetero)arenes. The methodology employs olefins and (hetero)arenes which are abundantly available chemical feedstocks, and could be applied in late-stage functionalization reactions of pharmaceuticals. Furthermore, the system exclusively delivers the allylic C-C coupling products highlighting the preservation of the olefin substitution pattern for further derivatization.