Literature DB >> 30151741

[Laser flare photometry for identification of high-risk patients for proliferative vitreoretinopathy].

F Schaub1, S Fauser2,3, B Kirchhof2, A Witte4, R Hörster5.   

Abstract

Proliferative vitreoretinopathy (PVR) is a complication of rhegmatogenous retinal detachment and trauma, which occurs in approximately 10% following vitreoretinal surgery. The visual prognosis for established PVR is poor and so far there is no established conservative treatment for PVR. In the currently recruiting PRIVENT trial the aim is to find a prophylactic treatment possibility for PVR. The PRIVENT study examines the influence of intraoperative adjuvant pharmacotherapy on reducing the incidence of PVR; however, this requires the identification of eyes with increased risk for PVR. Laser flare photometry is a simple method to predict the individual risk for PVR. It is a non-invasive technique that objectifies the Tyndall effect. Various laser flare meter devices are available on the market. In previous studies it could be shown that laser flare photometry can predict the development of PVR in eyes with primary rhegmatogenous retinal detachment with a sensitivity of 80%. The identification of these high-risk eyes for PVR could be the first step towards solving the problem of PVR.

Entities:  

Keywords:  PRIVENT study; Pharmacotherapy; Retinal detachment; Tyndall effect; Vision

Mesh:

Year:  2018        PMID: 30151741     DOI: 10.1007/s00347-018-0777-y

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  5 in total

Review 1.  [Proliferative Vitreoretinopathy: Therapeutic Strategies].

Authors:  F Schaub; P Enders; S Fauser
Journal:  Klin Monbl Augenheilkd       Date:  2016-08-01       Impact factor: 0.700

2.  Anterior chamber aqueous flare is a strong predictor for proliferative vitreoretinopathy in patients with rhegmatogenous retinal detachment.

Authors:  Sabine Schröder; Philipp S Muether; Albert Caramoy; Moritz Hahn; Medhat Abdel-Salam; Michael Diestelhorst; Bernd Kirchhof; Sascha Fauser
Journal:  Retina       Date:  2012-01       Impact factor: 4.256

Review 3.  [Proliferative vitreoretinopathy--pathogenesis and therapy].

Authors:  I Iandiev; A Bringmann; P Wiedemann
Journal:  Klin Monbl Augenheilkd       Date:  2010-03-16       Impact factor: 0.700

4.  Profibrotic cytokines in aqueous humour correlate with aqueous flare in patients with rhegmatogenous retinal detachment.

Authors:  Robert Hoerster; Manuel M Hermann; Andre Rosentreter; Philipp S Muether; Bernd Kirchhof; Sascha Fauser
Journal:  Br J Ophthalmol       Date:  2013-01-26       Impact factor: 4.638

5.  Proliferative vitreoretinopathy. The mechanism of development of vitreoretinal traction.

Authors:  B M Glaser; A Cardin; B Biscoe
Journal:  Ophthalmology       Date:  1987-04       Impact factor: 12.079

  5 in total
  1 in total

Review 1.  [Proliferative vitreoretinopathy prophylaxis : Mission (im)possible].

Authors:  F Schaub; A M Abdullatif; S Fauser
Journal:  Ophthalmologe       Date:  2021-01       Impact factor: 1.059

  1 in total

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