| Literature DB >> 30151514 |
Jiaoli Wang1, Jin Huang, Ke Quan, Jing Li, Yanan Wu, Qiaomei Wei, Xiaohai Yang, Kemin Wang.
Abstract
Direct imaging of low-abundance RNAs in live cells remains challenging because of the relatively low sensitivity of conventional molecular imaging probes. Here, we introduce hairpin-fuelled catalytic nanobeacons for microRNA (miRNA) imaging in live cells with signal amplification capacity. Compared with the conventional nanobeacons in solution, the catalytic nanobeacons could generate two orders of magnitude higher sensitivity.Mesh：
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Year: 2018 PMID： 30151514 DOI： 10.1039/c8cc06298f
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222