| Literature DB >> 30150734 |
Tracey Goldstein1, Simon J Anthony2,3,4, Aiah Gbakima5, Brian H Bird6, James Bangura5, Alexandre Tremeau-Bravard6, Manjunatha N Belaganahalli6, Heather L Wells7, Jasjeet K Dhanota6, Eliza Liang7,8, Michael Grodus7, Rohit K Jangra9, Veronica A DeJesus9, Gorka Lasso10, Brett R Smith6, Amara Jambai11, Brima O Kamara12, Sorie Kamara13, William Bangura14, Corina Monagin6,15, Sagi Shapira10,16, Christine K Johnson6, Karen Saylors15, Edward M Rubin15, Kartik Chandran9, W Ian Lipkin7,17, Jonna A K Mazet6.
Abstract
Here we describe the complete genome of a new ebolavirus, Bombali virus (BOMV) detected in free-tailed bats in Sierra Leone (little free-tailed (Chaerephon pumilus) and Angolan free-tailed (Mops condylurus)). The bats were found roosting inside houses, indicating the potential for human transmission. We show that the viral glycoprotein can mediate entry into human cells. However, further studies are required to investigate whether exposure has actually occurred or if BOMV is pathogenic in humans.Entities:
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Year: 2018 PMID： 30150734 PMCID： PMC6557442 DOI： 10.1038/s41564-018-0227-2
Source DB: PubMed Journal: Nat Microbiol ISSN： 2058-5276 Impact factor: 17.745