Literature DB >> 30150472

Implementation of Rapid Diagnostic Testing without Active Stewardship Team Notification for Gram-Positive Blood Cultures in a Community Teaching Hospital.

Paige M Bukowski1, Joshua S Jacoby2, Andrew P Jameson3,4, Lisa E Dumkow2.   

Abstract

In community hospitals, antimicrobial stewardship team notification of rapid diagnostic testing (RDT) results may not be feasible. A retrospective quasi-experimental study was conducted evaluating 252 adult inpatients with blood cultures positive for Gram-positive cocci in clusters (pre-RDT, n = 143; post-RDT, n = 109). The median time to appropriate therapy was significantly shorter in the post-RDT group (15 versus 0 h, P < 0.001), and the mean length of stay for patients with coagulase-negative staphylococcus was significantly shorter (10.5 versus 7.7 days; P = 0.015).
Copyright © 2018 American Society for Microbiology.

Entities:  

Keywords:  antimicrobial stewardship; bloodstream infections; coagulase-negative staphylococci; rapid diagnostic testing

Mesh:

Substances:

Year:  2018        PMID: 30150472      PMCID: PMC6201100          DOI: 10.1128/AAC.01334-18

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  7 in total

1.  An antimicrobial stewardship program's impact with rapid polymerase chain reaction methicillin-resistant Staphylococcus aureus/S. aureus blood culture test in patients with S. aureus bacteremia.

Authors:  Karri A Bauer; Jessica E West; Joan-Miquel Balada-Llasat; Preeti Pancholi; Kurt B Stevenson; Debra A Goff
Journal:  Clin Infect Dis       Date:  2010-11-01       Impact factor: 9.079

2.  Integrating rapid diagnostics and antimicrobial stewardship improves outcomes in patients with antibiotic-resistant Gram-negative bacteremia.

Authors:  Katherine K Perez; Randall J Olsen; William L Musick; Patricia L Cernoch; James R Davis; Leif E Peterson; James M Musser
Journal:  J Infect       Date:  2014-05-17       Impact factor: 6.072

3.  Impact of rapid identification of Staphylococcus aureus bloodstream infection without antimicrobial stewardship intervention on antibiotic optimization and clinical outcomes.

Authors:  R Brigg Turner; Karineh Lalikian; Madeline Fry; Jacqueline Schwartz; Dominic Chan; Regina Won
Journal:  Diagn Microbiol Infect Dis       Date:  2017-07-08       Impact factor: 2.803

4.  Impact of an assay that enables rapid determination of Staphylococcus species and their drug susceptibility on the treatment of patients with positive blood culture results.

Authors:  Mark Parta; Melanie Goebel; Jimmy Thomas; Mahsa Matloobi; Charles Stager; Daniel M Musher
Journal:  Infect Control Hosp Epidemiol       Date:  2010-10       Impact factor: 3.254

5.  Integrating rapid pathogen identification and antimicrobial stewardship significantly decreases hospital costs.

Authors:  Katherine K Perez; Randall J Olsen; William L Musick; Patricia L Cernoch; James R Davis; Geoffrey A Land; Leif E Peterson; James M Musser
Journal:  Arch Pathol Lab Med       Date:  2012-12-06       Impact factor: 5.534

6.  Impact of rapid organism identification via matrix-assisted laser desorption/ionization time-of-flight combined with antimicrobial stewardship team intervention in adult patients with bacteremia and candidemia.

Authors:  Angela M Huang; Duane Newton; Anjly Kunapuli; Tejal N Gandhi; Laraine L Washer; Jacqueline Isip; Curtis D Collins; Jerod L Nagel
Journal:  Clin Infect Dis       Date:  2013-07-29       Impact factor: 9.079

7.  Stewardship approach for optimizing antimicrobial therapy through use of a rapid microarray assay on blood cultures positive for Enterococcus species.

Authors:  Aaron Sango; Yvette S McCarter; Donald Johnson; Jason Ferreira; Nilmarie Guzman; Christopher A Jankowski
Journal:  J Clin Microbiol       Date:  2013-09-25       Impact factor: 5.948

  7 in total
  1 in total

Review 1.  Antimicrobial Stewardship Interventions to Combat Antibiotic Resistance: an Update on Targeted Strategies.

Authors:  Kelli A Cole; Kaitlyn R Rivard; Lisa E Dumkow
Journal:  Curr Infect Dis Rep       Date:  2019-08-31       Impact factor: 3.663

  1 in total

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